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Distraction helps kids get stitches in ER

Children's HealthApr 14 06

Listening to a CD player or playing a video game may make getting stitches more tolerable for children who come to the ER, new research suggests.

Previous reports have suggested beneficial effects using distraction techniques, but until now no studies have evaluated their ability to facilitate the completion of painful procedures in the pediatric ER setting.

As reported in the journal Pediatrics, Dr. Madhumita Sinha, from Maricopa Medical Center in Phoenix, Arizona, and colleagues assessed the outcomes of 240 children, between 6 and 18 years of age, who were randomly selected to receive a distractor or no distractor while receiving stitches. All of the children received a topical anesthetic and an injectable local anesthetic was given if deemed necessary.

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Lack of Basic Research Putting Patients at Risk

Emergencies / First AidApr 14 06

Patients are suffering because not enough basic clinical research is being done, warns a senior doctor in this week’s BMJ. He believes that medical academia is failing patients and clinicians by neglecting this vital area of research.

Basic observational research provides the information that doctors need to diagnose and treat patients appropriately, writes neurologist Professor Peter Rothwell. But in the field of neurology alone, many examples exist where a lack of basic data is the main barrier for effective treatment in routine practice.

For instance, little is known about the reliability of diagnosing stroke and, until very recently, no reliable data existed on the early risk of stroke in certain patients. Countless patients have suffered as a result, yet much of this research is easy and relatively cheap to do, so why has it not been done, he asks?

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Virus testing best for cervical cancer screening

CancerApr 14 06

An analysis of data for more than 60,000 women in North America and Europe suggests that testing for human papillomavirus (HPV) may be the best way to screen for cervical cancer.

Numerous reports have linked certain subtypes of HPV with the lesions that precede cervical cancer. Findings from individual studies have suggested that for initial screening, HPV testing is more sensitive than cytology, which involves an analysis of cervical cells taken during a Pap smear. However, firm conclusions could not be reached, due in part to differences in design between the studies.

In the current study, Dr. Jack Cuzick, from the Queen Mary School of Medicine in London, and colleagues analyzed data from all European and North American studies that included routine cytology and additional HPV testing as a parallel test.

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Cheap way to produce expensive malaria drug well on the way

Drug NewsApr 14 06

U.S. researchers say a cheap way to produce an expensive but effective malaria drug is well on the way.

The researchers have created a modified form of the yeast Saccharomyces cerevisiae that is capable of producing large amounts of artemisinic acid, which is needed to make the anti-malaria drug artemisinin.

Artemisinin is currently expensive to manufacture, and is out of reach for many in the developing world.

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U.S. expert says one wild bird does not make a pandemic

FluApr 14 06

U.S. expert says one wild bird does not make a pandemic, while Egypt finds bird flu case # 12

Egyptian health officials have reported another case of human bird flu in the country bringing the total there to date to 12.

According to Health and Population Minister Hatem el-Gabali the latest case is an 18-year-old woman from a province north of Cairo who caught the virus after handling infected birds.

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Self Harm High Among Goth Youths

Psychiatry / PsychologyApr 14 06

Rates of self harm and attempted suicide are high within Goth youth subculture, finds a study published on bmj.com today.

Deliberate self harm is common among young people, with rates of 7-14% in the UK. It is particularly widespread in certain populations and may be linked to depression, attempted suicide, and various psychiatric disorders in later life. Contemporary Goth youth subculture has been linked with self harm, but there is little evidence to support this.

Researchers at the University of Glasgow surveyed 1,258 young people during their final year of primary school (age 11) and again at ages 13, 15, and 19. They were asked about self harm and identification with a variety of youth subcultures, including Goth.

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Incontinent girls may suffer overactive bladder later

Urine ProblemsApr 13 06

Women who had urinary problems as children are more likely to have overactive bladder as adults, a new study shows.

The findings suggest that treating childhood urinary symptoms could prevent such problems in adulthood, Dr. Mary Pat Fitzgerald of Loyola University Medical Center in Maywood, Illinois and colleagues say.

The researchers surveyed 2,109 women aged 40 to 69, asking them about current urinary problems as well as whether they had such problems in childhood. Twenty-nine percent of the women reported having urinary incontinence, or leakage of urine, at least once a week, while 12 percent had daily incontinence.

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Imaging of breast cancer diagnosed and treated with chemotherapy during pregnancy

Breast CancerApr 13 06

Ultrasound provides a safe and accurate method of detecting breast cancers in pregnant women, as well as assessing response to chemotherapy, according to a study appearing in the April issue of Radiology.

Investigators at the M. D. Anderson Cancer Center in Houston recently studied the largest group of women to date who were both diagnosed and treated for breast cancer during pregnancy.

“Ultrasound identified 100 percent of cancers in our study, and mammography demonstrated 90 percent,” said Wei T. Yang, M.D., chief investigator of the study and associate professor of diagnostic radiology at the M. D. Anderson Cancer Center, Breast Imaging Section. “We want young women to know that symptomatic breast cancer that occurs during pregnancy can be imaged, diagnosed and treated while pregnant, so they should not wait to seek medical attention if they start to have suspicious symptoms.”

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Antibiotic may help asthma symptoms: study

AsthmaApr 13 06

An antibiotic made by French drug-maker Sanofi-Aventis may reduce some symptoms when asthma worsens but it does not improve breathing capacity, according to a study financed by the drug company.

The study published in this week’s New England Journal of Medicine found that 278 adults who took the antibiotic telithromycin—sold under the name Ketek—for 10 days after their attacks showed a drop in asthma symptoms.

But using another gauge of success—how much air patients could exhale—the antibiotic showed no benefit. “None of the pulmonary-function tests showed a significant treatment effect by the sixth week of the study,” the researchers concluded.

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Medicare rules hit heart device makers

HeartApr 13 06

Proposed rules changing the way the U.S. Medicare health insurance agency reimburses hospitals would hurt makers of pricey heart devices the most, and is most favorable to rural hospital companies, analysts said on Thursday.

The U.S. Centers for Medicare and Medicaid Services, a major source of hospital revenue, released draft rules late Wednesday with an aim to redistribute profits from highly reimbursed procedures such as some heart surgeries, to conditions seen as underpaid, like treating pneumonia.

The rules are subject to a public comment period and cover 2007 and 2008.

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Cholesterol-lowering drug might not promote healthy hearts

HeartApr 13 06

Antioxidants, such as beta-carotene and Vitamin E, have been touted for their ability to protect against heart disease.

This protective effect is attributed to their ability to prevent the oxidation of bad cholesterol by free radicals - a process thought to contribute to the build-up of disease-causing fatty deposits on artery walls. But a new study, published in The Journal of Experimental Medicine, suggests that the heart-healthy effect of one antioxidant has little to do with cholesterol oxidation.

A group of researchers at the University of New South Wales in Australia, led by Roland Stocker, studied a cholesterol-lowering drug called Probucol (Lorelco) in laboratory rodents with vascular disease. Probucol reduces the risk of heart disease in humans, but is no longer prescribed in the US and Australia because of adverse side effects: a tendency to lower good cholesterol along with the bad and the potential to induce an irregular heartbeat. Probucol is still available in Canada and Europe.

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Engineered yeast may cut cost of malaria drug

Public HealthApr 13 06

US researchers have created a modified form of the yeast Saccharomyces cerevisiae that is capable of producing large amounts of artemisinic acid, which is needed to make the anti-malaria drug artemisinin.

Malaria, caused by the one-celled parasite carried by mosquitoes called plasmodium, kills at least one million people every year and makes 300 million people seriously ill. Ninety percent of malaria deaths occur in Africa, south of the Sahara, mostly among young children.

Artemisinin is the drug of choice for treating multi-drug resistant strains of Plasmodium species. Unfortunately, the drug, which comes from the wormwood plant Artemisia annua, is expensive and supplies are limited, meaning that many malaria patients in developing countries go untreated.

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Early obesity raises risk of hip replacement later

ArthritisApr 13 06

Young adults who are overweight or obese may be particularly likely to need a hip replacement later in life, a large study suggests.

Using national data on 1.2 million adults, researchers in Norway found that those who were overweight or obese were at greater risk of eventually needing a total hip replacement due to severe arthritis. Men and women who were heavy before the age of 25 were especially at risk.

The findings underscore the importance of heading off excessive weight gain in childhood and adolescence, conclude the researchers, led by Dr. Gunnar Flugsrud of Ulleval University Hospital in Oslo. Their report is published in the journal Arthritis & Rheumatism.

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Delayed surgery decreases bladder cancer survival

CancerApr 13 06

For patients newly diagnosed with bladder cancer, delays of more than 3 months after the initial diagnosis to surgery results in decreased survival, a study shows.

“There currently are no standardized guidelines for the appropriate timing of cystectomy” (surgical removal of the bladder), Dr. Cheryl T. Lee from University of Michigan, Ann Arbor, Michigan told Reuters Health. “However, there is growing evidence that cystectomy should be performed within 3 months of a diagnosis” of muscle-invasive disease.

The current study, she said, supports that “patients must undergo cystectomy within 3 months of diagnosis or their survival may be compromised.”

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British woman wins Herceptin drug case

Breast CancerApr 13 06

A British woman with early-stage breast cancer won a legal appeal on Wednesday to force her local health authority to pay for the potentially life-saving drug Herceptin.

“I feel like I’ve won the lottery,” said Ann Marie Rogers, 54, who had called the initial decision by Swindon Primary Care Trust (PCT) not to give her the costly medication “a death sentence”.

The decision at London’s Court of Appeal overturned an earlier High Court ruling that said the PCT in Wiltshire did not have to pay for the drug, made by Switzerland’s Roche and which costs about 20,000 pounds ($35,000) a year.

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