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Tobacco & Marijuana

Teen smokers struggle to kick the habit; most want to quit and can’t

Children's Health • • Tobacco & MarijuanaJul 16 08

Most teenagers who smoke cigarettes make repeated attempts to quit but most are unsuccessful, according to new research from the Université de Montréal and funded by the Canadian Cancer Society.

“The study found that teen smokers make their first serious attempt to quit after only two and a half months of smoking, and by the time they have smoked for 21 months they have lost confidence in their ability to quit,” says Dr. Jennifer O’Loughlin, the study’s lead author and a researcher from the Université de Montréal’s department of social and preventive medicine.

Dr. O’Loughlin analyzed data from 319 Montreal teens who completed reports on their smoking habits every three months for five years. The study, published online (today) in the American Journal of Public Health, found that teen smokers progress through stages or milestones in their attempts to stop smoking. These stages are:

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Smoking linked to decrease in uterine cancer risk

Cancer • • Tobacco & MarijuanaJul 15 08

Cigarette smoking appears to be associated with a decreased risk of cancer of the endometrium, the inner lining of the uterus, research from China suggests.

“The benefit of smoking was observed almost exclusively in postmenopausal women and not in premenopausal women,” principal investigator Dr. Bin Wang of Nanjing Medical University told Reuters Health.

However, in spite of this link, “cigarette smoking could dramatically increase the incidence of many other chronic diseases,” Wang pointed out.

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Contests to Quit Smoking Don’t Work in Long Run

Tobacco & MarijuanaJul 15 08

Face it: we all have our price. Still, despite prizes ranging from lottery tickets to cash payments, quit-smoking contests do not help people kick the habit in the end, according to a new systematic review of studies.

None of the 17 studies, which involved roughly 6,300 participants, demonstrated significantly higher long-term quit rates for smokers offered incentives, despite some creative approaches.

In one study, participants were encouraged to toss their cigarettes down the toilet and rewarded with one lottery ticket per day. Another offered payments of $10 per month and participation in a monthly worksite lottery. Yet another offered cash prizes ranging from $100 to $250, along with certificates of recognition.

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Caregivers often expose asthmatic kids to smoke

Children's Health • • Asthma • • Tobacco & MarijuanaJul 02 08

Secondhand exposure to cigarette smoke is an asthma trigger in children and a new study shows that smoking by the primary caregiver and daycare provider are important sources of smoke exposure in children with asthma.

In the study, children with asthma who were exposed to secondhand smoke “had as much smoke exposure as if their mother smoked,” Dr. Harold J. Farber told Reuters Health.

Children with a double hit of smoke exposure - from both their daycare provider and primary caregiver - had the highest levels of nicotine metabolites in their urine, said Farber, of Texas Children’s Hospital in Houston.

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Treatment for cigarette, alcohol and drug use in pregnancy improves outcomes for mom and baby

Pregnancy • • Psychiatry / Psychology • • Tobacco & MarijuanaJun 26 08

Pregnant women who receive treatment for substance abuse early in their pregnancy can achieve the same health outcomes as pregnant women with no substance abuse, according to a Kaiser Permanente study published online in the Journal of Perinatology.

The study, which is the largest to date, examined 49,985 women in Kaiser Permanente’s prenatal care program and found that integrating substance abuse screening and treatment into routine prenatal care helped pregnant women achieve similar health outcomes as women who were not using cigarettes, alcohol or other drugs. This is also the largest study to examine multiple substances: cigarettes, alcohol, marijuana, methamphetamines, cocaine and heroin.

“This program can happen everywhere and should become the gold standard for women who are pregnant and using cigarettes, alcohol or other drugs,” said study lead author Nancy C. Goler, M.D., an OB/GYN and Kaiser Permanente regional medical director of the Early Start Program for the organization’s Northern California operations. “The study’s big finding was that study participants treated in the Early Start program had outcomes similar to our control group, women who had no evidence of substance abuse.”

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Fewer Heart Disease Deaths in Massachusetts as Smoking Declines

Heart • • Tobacco & MarijuanaJun 20 08

If more states introduce tobacco control programs for their residents who are regular smokers, the number of U.S. deaths due to coronary heart disease might drop, finds a new study that looks at an ongoing Massachusetts initiative.

A connection exists between coronary heart disease and cigarette smoking, and the new study determines how a reduction in smoking affected the number of related deaths in Massachusetts between 1993 and 2003. The state introduced its Massachusetts Tobacco Control Program (MTCP) in 1992, which received funding through a special cigarette tax, and the researchers say they expected to find it helped control the rate of smoking.

“California was the first state to have a statewide program like the MTCP and they witnessed substantial declines,” said lead author Zubair Kabir, M.D., who at the time of the study was a research fellow at the Harvard School of Public Health. “So it was not surprising that Massachusetts, the second state, would see such declines as well, which reflect the impact of a comprehensive, integrated and - at the time - well-funded program.”

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Lung cancer no more common in women smokers: study

Cancer • • Lung Cancer • • Tobacco & MarijuanaJun 16 08

Women who smoke are no more likely than men to get lung cancer but, among non-smokers, women appear to have a higher risk than men, U.S. researchers reported on Friday.

Women who had never smoked were 1.3 times more likely to develop lung cancer than men who had never smoked, Dr. Neal Freedman of the National Cancer Institute and colleagues found.

“We noted slightly higher age-standardized incidence rates of lung cancer in women who had never smoked than in men who had never smoked,” Freedman and colleagues wrote in the journal Lancet Oncology.

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Smoking in midlife may impair memory

Neurology • • Tobacco & MarijuanaJun 10 08

Middle-aged adults who smoke appear to have a higher than average risk of developing memory impairments, according to a report published in the Archives of Internal Medicine.

“With the aging population and the projected increases in older adults with dementia, it is important to identify modifiable risk factors,” lead author Dr. Severine Sabia told Reuters Health. “Our results suggest that smoking had an adverse effect on cognitive function in midlife. However, 10 years after smoking cessation, there is little adverse effect of smoking on cognition. Thus, public health messages should target smokers at all ages.”

In fact, long-term ex-smokers were less likely to have deficits in memory, vocabulary, and verbal fluency than those who never smoked. This “could be explained by improvement in other health behaviors among those giving up smoking in midlife,” said Sabia, a researcher with the Institut National de la Sante et de la Recherche Medicale in Villejuif, France.

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Report confirms increased risk of smoking, substance abuse in bipolar adolescents


A study from the Massachusetts General Hospital (MGH) supports previous reports that adolescents with bipolar disorder are at increased risk for smoking and substance abuse. The article appearing in the June Drug and Alcohol Dependence – describing the largest such investigation to date and the first to include a control group – also indicates that bipolar-associated risk is independent of the risk conferred by other disorders affecting study participants.

“This work confirms that bipolar disorder (BPD) in adolescents is a huge risk factor for smoking and substance abuse, as big a risk factor as is juvenile delinquency,” says Timothy Wilens, MD, director of Substance Abuse Services in MGH Pediatric Psychopharmacology, who led the study. “It indicates both that young people with BPD need to carefully be screened for smoking and for substance use and abuse and that adolescents known to abuse drugs and alcohol – especially those who binge use – should also be assessed for BPD.”

It has been estimated that up to 20 percent of children and adolescents treated for psychiatric problems have bipolar disorder, and there is evidence that pediatric and adolescent BPD may have features, such as particularly frequent and dramatic mood swings, not found in the adult form of the disorder. While elevated levels of smoking and substance abuse previously have been reported in young and adult BPD patients, it has not been clear how the use and abuse of substances relates to the presence of BPD or whether any increased risk could be attributed to co-existing conditions such as attention-deficit hyperactivity disorder (ADHD), conduct disorder or anxiety disorders.

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Second Hand Smoke Increases Hospital Admissions for All Types of Infectious Diseases

Infections • • Tobacco & MarijuanaMay 27 08

Children exposed to second hand tobacco smoke are more likely to get severe infectious diseases and have to be admitted to hospital, finds research published online ahead of print in Tobacco Control.

These children are at greater risk of a whole range of infectious illnesses, such as meningococcal disease, and not just respiratory illness, the results showed. Exposure to smoke in the first few months of life did the most harm, especially if they had a low birth weight or had been born prematurely.

The researchers assessed the relationship between second hand smoke exposure and first admission to hospital for any infectious illness for 7,402 children born in Hong Kong in April and May 1997. The children were followed until they were eight.

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Smokers quit in groups

Public Health • • Tobacco & MarijuanaMay 22 08

When smokers decide to kick the habit, odds are they are not alone in making that decision. New research shows that social ties play a key role in smoking behavior and if a close associate or relative, or even a distant one, stops smoking, a person’s odds of quitting increase.

“We’ve found that when you analyze large social networks, entire pockets of people who might not know each other all quit smoking at once,” Dr. Nicholas A. Christakis, from Harvard Medical School in Boston, who was involved in the study, said in a statement.

There has been a marked drop in smoking prevalence in the US and “network phenomena” are likely to be involved in this trend, Christakis and co-investigator Dr. James H. Fowler of the University of California, San Diego, note a report in Thursday’s issue of The New England Journal of Medicine.

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Tackle obesity like smoking: researcher

Obesity • • Tobacco & MarijuanaMay 14 08

Tackling the global obesity epidemic will require governments to take similar action to that many used to curb smoking, a top researcher said on Wednesday.

This could include regulations that restrict how companies market “junk” food to children and requirements for schools to serve healthy meals, said Professor Boyd Swinburn, a public health researcher who works with the World Health Organisation.

“The brakes on the obesity epidemic need to be policy-led and governments need to take centre stage,” Swinburn, a researcher at Deakin University in Australia, told Reuters at the 2008 European Congress on Obesity.

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OHSU Cancer Institute researchers pinpoint how smoking causes cancer

Cancer • • Lung Cancer • • Tobacco & MarijuanaMay 13 08

Oregon Health & Science University Cancer Institute researchers have pinpointed the protein that can lead to genetic changes that cause lung cancer.

The research will be published Tuesday, May 12, in the British Journal of Cancer.

Researchers discovered that the production of a protein called FANCD2 is slowed when lung cells are exposed to cigarette smoke. Low levels of FANCD2 leads to DNA damage, triggering cancer. Cigarette smoke curbs the production of ‘caretaker’ proteins, like FANCD2, which normally prevent cancer by fixing damages in DNA and causing faulty cells to commit suicide.

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Smoke, then Fire: Lung Cancer Screening Studies Under Further Scrutiny

Cancer • • Lung Cancer • • Tobacco & MarijuanaMay 06 08

In the January 2008 issue of The Oncologist, we reported that the authors of a controversial article on CT screening for early detection of lung cancer had not revealed their financial interests in screening software and biopsy instruments [1]. We considered these interests relevant to the message of the article, and hence decided not to make the article available as a Continuing Medical Education (CME) course [2]. It was further revealed by Paul Goldberg, editor of The Cancer Letter, that the same authors, Claudia Henschke and David Yankelevitz of Weill Cornell Medical College, had not disclosed these interests in their many previous articles published in the New England Journal of Medicine (NEJM), the Journal of the American Medical Association, and elsewhere [3].

Goldberg [4] and, independently, Gardiner Harris of The New York Times [5] reported on March 25 and March 26, 2008, respectively, that Henschke and Yankelevitz financed some of their lung cancer screening work with a $3.6 million grant from Vector, the parent company of the Liggett Group, a major cigarette manufacturer. The tobacco money was filtered through a nonprofit foundation, the Foundation for Lung Cancer Early Detection, Prevention & Treatment, that was hastily established in late 2000. Henschke, Yankelevitz, Antonio Gotto (dean of Weill Cornell Medical College and a noted cardiology researcher), and Arthur Mahon (chair of the Weill Cornell Board of Overseers) are the foundation’s officers and directors. The foundation’s support was acknowledged in a few articles published by these authors, but the origin of the money was not obvious to the journals, as recently observed by Jeffrey Drazen, the editor-in-chief of the NEJM [6]. Goldberg further documents that the authors subsequently accepted grant support from the American Cancer Society and other sources that specifically prohibit projects that receive funding from tobacco companies. In fact, the authors neither acknowledged this funding from Vector nor their foundation in the paper published by The Oncologist [7].

 

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Beijing says full smoking ban “impossible”

Tobacco & MarijuanaApr 24 08

Banning smoking completely in Beijing is “impossible” but the city will do its best to ensure a smoke-free environment for the Olympics through new regulations to come into force on May 1, officials said on Thursday.

The new regulations ban smoking in sports venues, parks, on public transport and in schools but restaurants and hotels are exempted.

The Olympic host city had pledged to restrict smoking in most public places before the August 8-24 Games and is committed to achieve a “thorough indoor smoke-free” environment required by the Framework Convention on Tobacco Control by 2011.

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