Stress
Stress tied to substance use among veterinarians
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High job stress may cause some veterinarians to turn to heavy drinking, smoking or medication to cope, a German study indicates.
In a survey of more than 2,000 veterinarians in Germany, the researchers found that 8 percent reported intense psychosocial stress, while another 45 percent said they had intermediate stress.
The team found that those under heavy stress were more likely than their counterparts to binge-drink or regularly use medications like painkillers and sedatives.
Transcendental Meditation buffers students against college stress: Study
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Transcendental Meditation may be an effective non-medicinal tool for students to buffer themselves against the intense stresses of college life, according to a new study to be published in the February 24 issue of the peer-reviewed International Journal of Psychophysiology.
“Effects of Transcendental Meditation practice on brain functioning and stress reactivity in college students” is the first random assignment study of the effects of meditation practice on brain and physiological functioning in college students.
The study was a collaboration between the American University Department of Psychology in Washington, D.C., and the Center for Brain, Consciousness, and Cognition at Maharishi University of Management in Fairfield, Iowa.
ARDS mortality is unchanged since 1994
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Mortality in patients with acute respiratory distress syndrome (ARDS) has not fallen since 1994, according to a comprehensive review of major studies that assessed ARDS deaths. This disappointing finding contradicts the common wisdom that ARDS mortality has been in steady decline.
The study was published in the first issue for February of the American Journal of Respiratory and Critical Care Medicine.
The authors reviewed all prospective observational and randomized controlled trials between 1984 and 2006 that included more than 50 ARDS/ALI patients and reported mortality.
Touching helps couples reduce stress
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Couples may be able to enhance one another’s health by being more physically affectionate with one another, new research in Psychosomatic Medicine shows.
Couples who underwent training in “warm touch enhancement” and practiced the technique at home had higher levels of oxytocin, also known as the “love hormone” and the “cuddle chemical,” while their levels of alpha amylase, a stress indicator, were reduced, Dr. Julianne Holt-Lunstad of Brigham Young University in Salt Lake City, Utah, and her colleagues found.
Emotional and social support is key to both mental and physical health, Holt-Lunstad and her team note, while support between spouses may be particularly vital. One important but little-studied way that people express this support, they add, is through “non-sexual, caring physical touch, such as hand-holding, hugs, and sitting or lying ‘cuddled up.’”
Cascading effect of even minor early problems may explain serious teen violence
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How do minor behavior problems and experiences early in life lead to serious acts of violence in teenagers? A group of researchers has found that the answer may lie in a cascading effect in which early life experiences lead to behaviors and new experiences that lead to yet other experiences that culminate in serious violent behavior.
The researchers found that children who had social and academic problems in elementary school were more likely to have parents who withdrew from supervision and monitoring when the children entered middle school. When this happened, children were more likely to make friends with other children who had deviant behavior, and this ultimately was more likely to lead teens to engage in serious and sometimes costly acts of violence. Interestingly, violent outcomes in girls followed largely the same developmental path as those for boys.
“The findings indicate that these trajectories are not inevitable but can be deflected at each subsequent era in development, through interactions with peers, school, and parents along the way,” notes Kenneth A. Dodge, William McDougall Professor of Public Policy and psychology and neuroscience, director of the Center for Child and Family Policy at Duke University, and the study’s lead author. “Successful early intervention could redirect paths of antisocial development to prevent serious violent behavior in adolescence.”
Obese have minimal heartbeat response to stress
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Contrary to their expectations, British researchers have found that when exposed to psychological stress, obese people show smaller changes in their heart rate compared with normal-weight individuals.
Dr. Douglas Carroll at the University of Birmingham, and colleagues there and at the University of Glasgow, examined the association between obesity and the magnitude of heart reactions to stress in 1,647 adults living in the community.
Blood pressure and heart rate were measured at rest and in response to psychological stress—performing mental math problems under a time deadline. Measurements were taken when the study began and 5 years later.
Chronic stress alters our genetic immune response
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Most people would agree that stress increases your risk for illness and this is particularly true for severe long-term stresses, such as caring for a family member with a chronic medical illness. However, we still have a relatively limited understanding of exactly how stress contributes to the risk for illness. In the August 15th issue of Biological Psychiatry, researchers shed new light on one link between stress and illness by describing a mechanism through which stress alters immune function.
In a very promising preliminary study, Miller and colleagues found that the pattern of gene expression differed between caregivers of family members with cancer relative to a matched group of individuals who did not have this type of life stress. They found that among the caregivers, even though they had normal cortisol levels in their blood, the pattern of gene expression in the monocytes, a type of white blood cell involved in the body’s immune response, was altered so that they were relatively less responsive to the anti-inflammatory actions of cortisol, but relatively more responsive to pro-inflammatory actions of a transcription factor called nuclear factor-kappa B, or NF-κB. Gregory Miller, Ph.D., corresponding author, explains more simply that, although “caregivers have similar cortisol levels as controls, their cells seem to be ‘hearing’ less of this signal. In other words, something goes awry in caregivers’ white blood cells so they are not able to ‘receive’ the signal from cortisol that tells them to shut down inflammation.”
Thus, the current findings might help to explain why the caregivers would seem to be in a chronic pro-inflammatory state, a condition of immunologic activation. This activated state could contribute to the risk for a number of medical illnesses, such as depression, heart disease, and diabetes. Dr. Miller remarks that part of the importance of these findings is “because people have traditionally thought that higher cortisol is the reason that stress contributes to disease, but this work shows that, at least in caregivers, it’s actually the opposite - there’s too little cortisol signal being heard by the cells, rather than too much.”
High Resolution Heart Images Now Available at Peak Stress
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While treadmill exercise stress testing is an essential tool in the prevention, detection and treatment of cardiovascular disease, physicians are often challenged to gain clear images of the heart when a patient is at peak stress level.
That is changing at the Ohio State University Medical Center where researchers have designed equipment to provide high resolution images of the heart at a critical stage of testing that have previously been difficult to obtain using standard testing procedures. Superior images of the heart are obtained with a test lasting less than one hour.
“In the past, we were constrained by the time lapse between the completion of exercise and capturing the images,” said Orlando “Lon” Simonetti, PhD, associate professor of internal medicine and radiology.
Measuring the stress of forested areas
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Plants undergo stress because of lack of water, due to the heat or the cold or to excess of light. A research team from the University of the Basque Country have analysed the substances that are triggered in plants to protect themselves, with the goal of choosing the species that is best suited to the environment during reforestation under adverse environmental conditions.
Droughts, extreme temperatures, contamination, and so on – all are harmful to plants. On occasions, the damage is caused by humans. For example, as a consequence of cutting down trees, plants used to shady conditions may be exposed to an excess of light. However, in most cases it is nature itself that causes the stress. In spring, plants have sufficient average humidity and temperatures, i.e. what scientists deem ‘optimum conditions’. But in winter they have to withstand considerable cold and in summer, on the other hand, high temperatures and droughts: adverse environmental factors that generate stress situations. Thus, in winter and in summer, the light which under normal conditions would be a source of energy becomes excessive, given that the metabolism of the plants under these conditions is not able to assimilate it. This process is known as photo-oxidative stress.
Neurogenesis in the adult brain: The association with stress and depression
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The brain is the key organ in the response to stress. Brain reactions determine what in the world is threatening and might be stressful for us, and regulate the stress responses that can be either adaptive or maladaptive. Chronic stress can affect the brain and lead into depression: Environmental stressors related to job or family situation are important triggers of depressive episodes and major life events such as trauma or abuse amongst the most potent factors inducing depression.
The World Health Organization (WHO) predicts that major depression will soon be the world´s greatest public health burden. Thus optimising antidepressive therapy with regard to delayed or insufficient treatment response and unwanted side effects is urgent.
Since the development of novel antidepressants is based upon an improved neurobiological understanding of this condition, new information about the cellular changes that take place in the brain is required.
Stress May Lead Students to Stimulants
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The performance pressures from end-of-semester exams and papers can take a toll on students, even leading them to turn to potentially harmful substances to keep them awake and alert.
Recent studies show that a growing number of high school and college students are turning to stimulants like ADHD (Attention Deficit Hyperactivity Disorder) drugs and energy drinks to help them through their stress — particularly during exam time, says Jennifer Christner, M.D., an adolescent medicine specialist at the University of Michigan Health System.
“Studies have shown that anywhere from 5 to 35 percent of college students are misusing stimulants around stressful times with academics. There is also some evidence that high school students — anywhere from 8 to 10 percent — can misuse stimulants during these times,” she says.
Psychological Distress, Not Depression, Linked to Increased Risk of Stroke
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Psychological distress, but not depression, may increase the risk of stroke, according to a study published in the March 4, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology. Previous studies have shown that stroke often leads to depression, but the evidence was mixed as to whether depression could lead to stroke.
“Stroke is among the leading causes of long-term disability and death worldwide,” said study author Paul Surtees, PhD, of the University of Cambridge in the United Kingdom. “Understanding the mechanisms by which overall emotional health may increase stroke risk may inform stroke prevention and help identify those at increased stroke risk.”
Stress hormone impacts memory, learning in diabetic rodents
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Diabetes is known to impair the cognitive health of people, but now scientists have identified one potential mechanism underlying these learning and memory problems. A new National Institutes of Health (NIH) study in diabetic rodents finds that increased levels of a stress hormone produced by the adrenal gland disrupt the healthy functioning of the hippocampus, the region of the brain responsible for learning and short-term memory. Moreover, when levels of the adrenal glucocorticoid hormone corticosterone (also known as cortisol in humans) are returned to normal, the hippocampus recovers its ability to build new cells and regains the “plasticity” needed to compensate for injury and disease and adjust to change.
The study appears in the Feb. 17, 2008, issue of Nature Neuroscience and was conducted by the National Institute on Aging (NIA), part of the NIH. NIA’s Mark Mattson, Ph.D., and colleagues in the Institute’s Intramural Research Program performed the study with Alexis M. Stranahan, a graduate student at Princeton University in New Jersey.
“This research in animal models is intriguing, suggesting the possibility of novel approaches in preventing and treating cognitive impairment by maintaining normal levels of glucocorticoid,” said Richard J. Hodes, M.D., NIA director. “Further study will provide a better understanding of the often complex interplay between the nervous system, hormones and cognitive health.”
Workplace opportunities and stresses are both increasing
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Teamworking and other modern employment practices can put as much strain on a woman’s family relationships as working an extra 120 hours a year, an extensive study of the British workforce funded by the Economic and Social Research Council suggests.
The research finds that while British employers have maintained long-term career relationships with employees in spite of competitive market pressures, they have devised ways of extracting more effort and higher performance. These practices include team-based forms of work organization, individual performance-related pay, and policies that emphasize the development of individual potential.
Floating effective for stress and pain
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Relaxation in large, sound- and light-proof tanks with high-salt waterfloatingis an effective way to alleviate long-term stress-related pain. This has been shown by Sven-Åke Bood, who recently completed his doctorate in psychology, with a dissertation from Karlstad University in Sweden.
The dissertation confirms what earlier studies have indicated: sleep was improved, patients felt more optimistic, and the content of the vitalizing hormone prolactin increased. Anxiety, stress, depression, and perception of pain declined.
