Acetaminophen and Salicylates (Systemic)

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur :

Less common or rare

Coughing; difficulty in swallowing; dizziness, lightheadedness, or feeling faint (severe); flushing, redness, or other change in skin color; shortness of breath, troubled breathing, tightness in chest, or wheezing; sudden decrease in amount of urine; swelling of eyelids, face, or lips

Signs and symptoms of overdose

Agitation, anxiety, excitement, irritability, nervousness, or restlessness; any loss of hearing; bloody urine; confusion or delirium; convulsions (seizures); diarrhea (severe or continuing); dizziness or lightheadedness; drowsiness (severe); fast or deep breathing; fast or irregular heartbeat (for medicines containing caffeine); fever; frequent urination (for medicines containing caffeine); hallucinations (seeing, hearing, or feeling things that are not there); headache (severe or continuing); increased sensitivity to touch or pain (for medicines containing caffeine); increased sweating; increased thirst; loss of appetite; muscle trembling or twitching (for medicines containing caffeine); nausea or vomiting (continuing, sometimes with blood); ringing or buzzing in ears (continuing); seeing flashes of �zig-zag� lights (for medicines containing caffeine); stomach cramps or pain (severe or continuing); swelling, pain, or tenderness in the upper abdomen or stomach area; trouble in sleeping (for medicines containing caffeine); uncontrollable flapping movements of the hands, especially in elderly patients; unexplained fever; vision problems

Signs of overdose in children

Changes in behavior; drowsiness or tiredness (severe); fast or deep breathing

Also, check with your doctor as soon as possible if any of the following side effects occur:

Less common or rare

Bloody or black, tarry stools; bloody or cloudy urine; fever with or without chills (not present before treatment and not caused by the condition being treated); pain in lower back and/or side (severe and/or sharp); pinpoint red spots on skin; skin rash, hives, or itching; sores, ulcers, or white spots on lips or in mouth; sore throat (not present before treatment and not caused by the condition being treated); stuffy nose; swelling of face, fingers, feet, or lower legs; unusual bleeding or bruising; unusual tiredness or weakness; vomiting of blood or material that looks like coffee grounds; weight gain; yellow eyes or skin

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Heartburn or indigestion (for medicines containing aspirin); nausea, vomiting, or stomach pain (for medicines containing aspirin)

Less common

Drowsiness (for medicines containing salicylamide); trouble in sleeping, nervousness, or jitters (for medicines containing caffeine)

Some side effects may occur after you have stopped taking these combination medicines, especially if you have taken large amounts of them for a long time. Check with your doctor immediately if any of these side effects occur after you have stopped taking these medicines:

Rare

Bloody or cloudy urine; decreased urination; swelling of face, fingers, feet, or lower legs; weight gain

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.