Adalimumab (Systemic)

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These may include certain types of cancer, such as bladder or skin cancer. Discuss these possible effects with your doctor.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal fullness; body aches or pain; cough or hoarseness; ear congestion; gaseous abdominal pain; infection; lightheadedness

loss of voice; lower back or side pain; muscle aches and pains; nasal congestion; pain or tenderness around eyes or cheekbones; rapid sometimes shallow breathing; runny nose; shivering; stuffy nose; sunken eyes; thirst; trouble sleeping; warmth on skin; wrinkled skin

Less common

Abdominal pain; abnormal vaginal bleeding or discharge; agitation; anxiety; arm, back, or jaw pain; a sore on the skin of the breast that doesn't heal; back pain; black, tarry stools; bleeding from gums or nose; blindness; bloating or swelling of face, arms, hands, lower legs, or feet; blood in stool or change in bowel habits; bloody or cloudy urine; blurred vision; broken bones; change in size, shape, or color of an existing mole; change in skin color; chest tightness or heaviness; chest pain; chills; clear or bloody discharge from nipple; cold hands and feet; confusion; constipation; cough; coughing or spitting up blood; decreased urination; decreased vision; depression; difficulty, burning, or painful urination; difficult or frequent urination; dimpling of breast skin; difficulty breathing; drowsiness; eye pain; fainting; fast, slow or irregular heartbeat; fever; forgetfulness; frequent urge to urinate; general feeling of illness; hair loss; hallucinations; headache; increased thirst; inverted nipple; irregular breathing; irregular pulse; irritability; itching; light colored stools; loss of appetite; lump in breast or under your arm; lump or swelling in the abdomen; mole that leaks fluid or bleeds; mood or mental changes; muscle cramps or spasms; nausea; new mole; night sweats; no blood pressure or pulse; noisy breathing; numbness or tingling in your arms, legs, or face; pain, redness, or swelling in arms or legs without any injury present; pale skin; persistent non-healing sore on your skin; pink growth; raised, firm, bright red patch; rash; redness or swelling of the breast; seizures; sharp back pain just below your ribs; shiny bump on your skin; shortness of breath; slurred speech or problems swallowing; sneezing; sore throat; sores, ulcers, or white spots on lips or mouth; spitting up blood; stiff neck; stopping of the heart; sudden high fever or low grade fever for months; sweating; swelling of the face, fingers, feet, or lower legs; swollen glands; swollen neck veins; tightness in chest; tiredness; trouble breathing with activity; trouble thinking; unconsciousness; unexplained bruising or bleeding; unpleasant breath odor; unusual tiredness or weakness; unusual weight gain or loss; visual disturbances; vomiting; vomiting of blood or material that looks like coffee grounds; yellow skin or eyes

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.

More Common

Bladder pain; bleeding; blistering; burning; coldness; discoloration of skin; feeling of pressure; general feeling of discomfort or illness; hives; infection; inflammation; joint pain; large amount of cholesterol in your blood; large amount of fat in your blood; lumps; numbness; pounding in the ears; redness; scarring; soreness; stinging; swelling; tenderness; tingling; ulceration; warmth

Less common

Abnormal healing; decrease in height; difficulty in moving; difficulty in walking; difficulty swallowing; dry mouth; heartburn; indigestion; loss of hearing; loss of strength or energy; menstrual changes; muscle or joint stiffness, tightness, or rigidity; muscle pain or stiffness; muscle pain or weakness; pain in back, ribs, arms, or legs; pain or burning in throat; passing of gas; shakiness in legs, arms, hands, and feet; sores; stomach pain, fullness, or discomfort; swelling or redness in joints; weakness

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.