Anticholinergics/Antispasmodics (Systemic)

Proper Use of This Medicine

Take this medicine only as directed . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Dosing - The dose of the anticholinergic/antispasmodic will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of your medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The number of capsules or tablets or teaspoonfuls of solution or syrup that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depends on the medical problem for which you are taking this medicine .

For anisotropine
• For oral dosage forms (tablets):
  • To treat duodenal or stomach ulcers:
    • Older adults, adults, and teenagers - 50 milligrams (mg) three times a day. Your doctor may change the dose if needed.
    • Children - Dose must be determined by your doctor.

For atropine
• For oral dosage form (tablets):
  • To treat duodenal or stomach ulcers, intestine problems, or urinary problems:
    • Older adults, adults, and teenagers - 300 to 1200 micrograms (mcg) every four to six hours.
    • Children - Dose is based on body weight. The usual dose is 10 mcg per kilogram (kg) (4.5 mcg per pound) of body weight every four to six hours. However, the dose will not be more than 400 mcg every four to six hours.
• For injectable dosage form:
  • To treat duodenal or stomach ulcers or intestine problems:
    • Older adults, adults, and teenagers - 400 to 600 mcg injected into a muscle, vein, or under the skin every four to six hours.
    • Children - The dose is based on body weight. The usual dose is 10 mcg per kilogram (kg) (4.5 mcg per pound) of body weight injected under the skin every four to six hours. However, the dose will not be more than 400 mcg every four to six hours.
  • To treat heart problems:
    • Older adults, adults, and teenagers - 400 to 1000 mcg injected into a vein every one to two hours as needed. The total dose will not be more than 2 mg.
    • Children - The dose is based on body weight. The usual dose is 10 to 30 mcg per kilogram (kg) (4.5 to 13.6 mcg per pound) of body weight injected under the skin.

For belladonna
• For oral dosage form (oral solution):
  • To treat duodenal or stomach ulcers or intestine problems:
    • Older adults, adults, and teenagers - 180 to 300 micrograms (mcg) three or four times a day. The dose should be taken 30 to 60 minutes before meals and at bedtime. Your doctor may change the dose if needed.
    • Children - The dose is based on body weight. The usual dose is 9 mcg per kilogram (kg) (4 mcg per pound) of body weight three or four times a day.

For clidinium
• For oral dosage form (capsules):
  • To treat duodenal or stomach ulcers:
    • Older adults, adults, and teenagers - 2.5 to 5 milligrams (mg) three or four times a day. The dose should be taken before meals and at bedtime. Your doctor may change the dose if needed.
    • Children - Dose must be determined by your doctor.

For dicyclomine
• For oral dosage forms (capsules, extended-release tablets, syrup, tablets):
  • To treat intestine problems:
    • Older adults, adults, and teenagers - 10 to 20 milligrams (mg) three or four times a day. Some people may take 30 mg two times a day. Your doctor may change the dose if needed. Your dose will not be more than 160 mg a day.
    • Children 2 years of age and older - 5 to 10 mg three or four times a day. Your doctor may change the dose if needed.
    • Children 6 months to 2 years of age - 5 to 10 mg of the syrup three or four times a day. Your doctor may change the dose if needed.
    • Children up to 6 months of age - Use is not recommended.
• For injectable dosage form:
  • To treat intestine problems:
    • Older adults, adults, and teenagers - 20 mg injected into a muscle every four to six hours. Your doctor may change the dose if needed.
    • Children - Dose must be determined by your doctor.

For glycopyrrolate
• For oral dosage form (tablets):
  • To treat duodenal or stomach ulcers:
    • Older adults, adults, and teenagers - To start, 1 to 2 milligrams (mg) two or three times a day. Some people may also take 2 mg at bedtime. Your doctor may change the dose if needed. However, your dose will not be more than 8 mg a day.
    • Children - Dose must be determined by your doctor.
• For injectable dosage form:
  • To treat duodenal or stomach ulcers:
    • Older adults, adults, and teenagers - 100 to 200 micrograms (mcg) injected into a muscle or vein. The dose may be repeated every four hours up to four times a day.
    • Children - Dose must be determined by your doctor.

For homatropine
• For oral dosage form:
  • To treat duodenal or stomach ulcers:
    • Older adults, adults, and teenagers - 5 to 10 milligrams (mg) three or four times a day. Your doctor may change the dose if needed.
    • Children - Dose must be determined by your doctor.

For hyoscyamine
• For oral dosage forms (capsules, elixir, oral solution, tablets):
  • To treat duodenal or stomach ulcers, intestine problems, or urinary problems:
    • Older adults, adults, and teenagers - 125 to 500 micrograms (mcg) four to six times a day. Some people may take 375 mcg two times a day. The tablets should be taken 30 to 60 minutes before meals. Your doctor may change the dose if needed.
    • Children - Dose is based on body weight. The usual dose is 12.5 to 187 mcg every four hours if needed.
• For injectable dosage form:
  • To treat duodenal or stomach ulcers or intestine problems:
    • Older adults, adults, and teenagers - 250 to 500 mcg injected into a muscle, vein, or under the skin every four to six hours.
    • Children - Dose must be determined by your doctor.

For mepenzolate
• For oral dosage form (tablets):
  • To treat duodenal or stomach ulcers or intestine problems:
    • Older adults, adults, and teenagers - 25 to 50 milligrams (mg) four times a day, with meals and at bedtime. Your doctor may change the dose if needed.
    • Children - Dose must be determined by your doctor.

For methantheline
• For oral dosage form (tablets):
  • To treat intestine or stomach ulcers, intestine problems, or urinary problems:
    • Older adults, adults, and teenagers - 50 to 100 milligrams (mg) every six hours. Your doctor may change the dose if needed.
    • Children 1 year of age and older - 12.5 to 50 mg four times a day. Your doctor may change the dose if needed.
    • Children 1 month to 1 year of age - 12.5 mg four times a day. Your doctor may change the dose if needed.
    • Children up to 1 month of age - 12.5 mg two times a day. Your doctor may change the dose if needed.

For methscopolamine
• For oral dosage form (tablets):
  • To treat duodenal or stomach ulcers or intestine problems:
    • Older adults, adults, and teenagers - 2.5 to 5 milligrams (mg) four times a day, one-half hour before meals and at bedtime. Your doctor may change the dose if needed.
    • Children - Dose is based on body weight. The usual dose is 200 micrograms (mcg) per kilogram (kg) (90.9 mcg per pound) of body weight four times a day. The dose should be taken before meals and at bedtime.

For pirenzepine
• For oral dosage form (tablets):
  • To treat duodenal or stomach ulcers or intestine problems:
    • Older adults, adults, and teenagers - 50 milligrams (mg) two times a day, in the morning and at bedtime. Your doctor may change the dose if needed.
    • Children - Dose must be determined by your doctor.

For propantheline
• For oral dosage form (tablets):
  • To treat duodenal or stomach ulcers:
    • Older adults, adults, and teenagers - 7.5 to 15 milligrams (mg) three times a day, one-half hour before meals, and 30 mg at bedtime. Your doctor may change the dose if needed.
    • Children - Dose is based on body weight. The usual dose is 375 micrograms (mcg) per kilogram (kg) (170 mcg per pound) of body weight four times a day. Your doctor may change the dose if needed.

For scopolamine
• For oral dosage form (tablets):
  • To treat urinary problems or intestine problems or painful menstruation:
    • Older adults, adults, and teenagers - 10 to 20 milligrams (mg) three or four times a day. Your doctor may change the dose if needed.
    • Children - Dose must be determined by your doctor.
• For injectable dosage form:
  • To treat urinary problems or intestine problems:
    • Older adults, adults, and teenagers - 10 to 20 mg three or four times a day. Your doctor may change the dose if needed.
    • Children - Dose must be determined by your doctor.
• For rectal dosage form (suppository):
  • To treat urinary problems or intestine problems or painful menstruation:
    • Older adults, adults, and teenagers - Insert one 10 mg suppository rectally three or four times a day. Your doctor may change the dose if needed.
    • Children - Dose must be determined by your doctor.
• For transdermal dosage form (patch):
  • To treat motion sickness:
    • Older adults, adults, and teenagers - Apply one 1.0 milligram (mg) patch behind ear at least four hours before antinausea effect is needed.
    • Children - Use is not recommended.
  • To treat nausea and vomiting after surgery
    • Older adults, adults and teenagers - Apply one 1.0 mg patch behind the ear the evening before surgery to prevent nausea and vomiting after surgery
    • Children - Use is not recommended.

Missed dose - If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

For patients taking any of these medicines by mouth :

• Take this medicine 30 minutes to 1 hour before meals unless otherwise directed by your doctor.

To use the rectal suppository form of scopolamine :

• If the suppository is too soft to insert, chill it in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.
• To insert the suppository: First remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum.

To use the transdermal disk form of scopolamine :

• This medicine usually comes with patient directions. Read them carefully before using this medicine.
• Wash and dry your hands thoroughly before and after handling.
• Apply the disk to the hairless area of skin behind the ear. Do not place over any cuts or irritations.

Storage - To store this medicine:

• Keep out of the reach of children. Overdose is especially dangerous in young children.
• Store away from heat and direct light.
• Do not store the capsule or tablet form of this medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Keep the liquid form of this medicine tightly closed and keep it from freezing. Do not refrigerate the syrup form of this medicine.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.