Cycloserine (Systemic)

Brand Names : Seromycin

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For cycloserine, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to cycloserine. Also, tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy - Cycloserine has not been shown to cause birth defects or other problems in humans.

Breast-feeding - Cycloserine passes into the breast milk. However, cycloserine has not been reported to cause problems in nursing babies.

Children - Although there is no specific information comparing use of cycloserine in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.

Older adults - Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of cycloserine in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking cycloserine, it is especially important that your health care professional know if you are taking the following:

• Ethionamide (e.g., Trecator-SC) - Ethionamide may increase the risk of nervous system side effects, especially seizures

Other medical problems - The presence of other medical problems may affect the use of cycloserine. Make sure you tell your doctor if you have any other medical problems, especially:

• Alcohol abuse (or history of) or
• Convulsive disorders such as seizures or epilepsy - Cycloserine may increase the risk of seizures in patients who drink alcohol or have a history of seizures

• Kidney disease - Cycloserine is removed from the body through the kidneys, and patients with kidney disease may need an adjustment in dose or the medicine may need to be discontinued

• Mental disorders such as mental depression, psychosis, or severe anxiety - Cycloserine may cause anxiety, mental depression, or psychosis