Daclizumab (Systemic)

Brand Names : Zenapax, dacliximab

Before Using This Medicine

In deciding to use a medicine, the risks of receiving the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For daclizumab, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to daclizumab. Also tell your health care professional if you are allergic to any other substances.

Pregnancy - Daclizumab crosses the placenta. However, daclizumab has not been studied in pregnant women.

Breast-feeding - It is not known if daclizumab passes into breast milk. Breast-feeding is not recommended for patients receiving daclizumab.

Children - Studies on the use of daclizumab in children have not been completed. However, daclizumab may cause high blood pressure and dehydration more often in children than it does in adults.

Older adults - Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of daclizumab in the elderly with use in other age groups.

Other medical problems - The presence of other medical problems may affect the use of daclizumab. Make sure you tell your doctor if you have any other medical problems, especially:

• Cancer - Daclizumab may make this condition worse

• Diabetes mellitus (sugar diabetes) - Daclizumab can increase the amount of sugar in the blood

• Infection - Daclizumab may decrease the body's ability to fight infection