Dezocine (Systemic)

Brand Names : Dalgan

Before Using This Medicine

In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For dezocine, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to dezocine. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy - Studies on birth defects with dezocine have not been done in pregnant women. Dezocine did not cause birth defects in animal studies. However, the birth weights of the newborn animals were lower than normal, probably because the pregnant animals ate less than usual.

Too much use of a narcotic during pregnancy may cause the baby to become dependent on the medicine. This may lead to withdrawal side effects after birth. Also, narcotics may cause breathing problems in the newborn infant if taken just before delivery.

Breast-feeding - It is not known whether dezocine passes into the breast milk. However, it has not been reported to cause problems in nursing babies.

Children - Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of dezocine in patients up to 18 years of age with use in other age groups.

Older adults - Elderly people are especially sensitive to the effects of narcotic analgesics such as dezocine. This may increase the chance of side effects, especially breathing problems, during treatment.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are using dezocine, it is especially important that your health care professional know if you are taking any of the following:

• Central nervous system (CNS) depressants, including other narcotics, or
• Tricyclic antidepressants (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil]) - The chance of side effects may be increased

• Naltrexone (e.g., Trexan) - Dezocine may not be effective in people taking naltrexone

Other medical problems - The presence of other medical problems may affect the use of dezocine. Make sure you tell your doctor if you have any other medical problems, especially:

• Alcohol abuse, or history of, or
• Drug dependence, especially narcotic abuse, or history of, or
• Emotional problems - The chance of side effects may be increased; also, withdrawal symptoms may occur if a narcotic you are dependent on is replaced by dezocine

• Brain disease or head injury or
• Colitis or other intestinal disease or
• Diarrhea or
• Emphysema, asthma, or other chronic lung disease or
• Enlarged prostate or problems with urination - Some of the side effects of narcotic analgesics can be dangerous if these conditions are present

• Heart or blood vessel disease, severe, or
• Gallbladder disease or gallstones or
• Kidney disease or
• Liver disease or
• Underactive thyroid - The chance of side effects may be increased