Diclofenac and Misoprostol (Systemic)

Brand Names : Arthrotec 50, Arthrotec 75

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

Black, tarry stools; bleeding or crusting sores on lips; blood in urine or stools; bruises and/or red spots on the skin; chest pain; chills; confusion; continuing thirst; convulsions (seizures); cough or hoarseness; disorientation; drowsiness; fainting; fever with or without chills; fluid retention; general feeling of illness; heartburn and/or indigestion; increased blood pressure; increased heart rate; increased weight gain; itching of the skin; irregular heartbeat; large, flat, blue or purplish patches on the skin; light-headedness or dizziness; lower back or side pain; mental depression; muscle cramps; nausea; painful or difficult urination; pounding heartbeat; psychotic reaction; rectal bleeding; seeing, hearing, or feeling things that are not there; severe headache; severe hepatic reactions; severe stomach pain, cramping or burning; shortness of breath, troubled breathing, tightness in chest, and/or wheezing; skin rash; sores, ulcers, or white spots on lips or in mouth; sore throat; stiff neck and/or back; sudden decrease in the amount of urine; swelling and/or tenderness in upper stomach; swelling of face, fingers, feet, and/or lower legs; unusual bleeding or bruising; unusual tiredness or weakness; vomiting of material that looks like coffee grounds; yellow eyes or skin

Rare

Changes in facial skin color; fast or irregular breathing; puffiness or swelling of the eyelids or around the eyes

Symptoms of overdose

Confusion; diarrhea; drowsiness; fever; nausea and/or vomiting; pounding heartbeat; convulsions (seizures); shortness of breath; slow heartbeat; stomach pain; trembling or shaking

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Diarrhea; gas; heartburn

Less common

Abnormal vision; acne; change in sense of taste; decreased appetite; dry mouth; irritability or nervousness; loss of hair; muscle pain; decrease in sexual ability; tingling, burning, or prickling sensations; trembling or shaking; trouble swallowing; vaginal bleeding

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.