Isoniazid and Thiacetazone (Systemic)

Brand Names : INAT, Thiazina, Thisozide, INH, thioacetazone, amithiozone

Precautions While Using This Medicine

It is very important that your doctor or health care worker check your progress at regular visits. Also, check with your doctor or health care worker immediately if blurred vision or loss of vision, with or without eye pain, occurs during treatment . Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

It is also very important to check with your doctor or health care worker immediately if you develop any kind of rash . This medicine may cause a very serious rash in any patient, but it occurs more often in patients with human immunodeficiency virus (HIV) infection. If you notice a rash, stop taking this medicine and see your health care worker immediately.

If your symptoms do not improve within 2 to 3 weeks, or if they become worse, check with your doctor or health care worker.

Certain foods such as cheese (Swiss or Cheshire) or fish (tuna, skipjack, or Sardinella) may rarely cause reactions in some patients taking isoniazid and thiacetazone combination. Check with your doctor or health care worker if redness or itching of the skin, hot feeling, fast or pounding heartbeat, sweating, chills or clammy feeling, headache, or lightheadedness occurs while you are taking this medicine.

Liver problems may be more likely to occur if you drink alcoholic beverages regularly while you are taking this medicine. Also, the regular use of alcohol may keep this medicine from working properly. Therefore, you should strictly limit the amount of alcoholic beverages you drink while you are taking isoniazid and thiacetazone combination .

If this medicine causes you to feel very tired or very weak or causes clumsiness; unsteadiness; a loss of appetite; nausea; numbness, tingling, burning, or pain in the hands and feet; or vomiting, check with your health care worker immediately . These may be early warning signs of serious liver or nerve problems.

For diabetic patients:
• This medicine may affect the results of some urine sugar tests . Check with your doctor or health care worker before changing your diet or the dosage of your diabetes medicine.