Molindone (Systemic)

Brand Names : Moban, Moban Concentrate

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For molindone, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to molindone, phenothiazines, thioxanthenes, haloperidol, or loxapine. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy - Molindone has not been shown to cause birth defects or other problems in humans. However, studies in mice have shown a slight decrease in successful pregnancies.

Breast-feeding - It is not known if molindone passes into breast milk.

Children - Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of molindone in children with use in other age groups.

Older adults - Elderly patients are usually more sensitive than younger adults to the effects of molindone. Constipation, dizziness or lightheadedness, drowsiness, dryness of mouth, trembling of the hands and fingers, and symptoms of tardive dyskinesia (such as rapid, worm-like movements of the tongue or any other uncontrolled movements of the mouth, tongue, or jaw, and/or arms and legs) are especially likely to occur in elderly patients.

Other medicines - Although certain medicines should not be used together at all, in other cases 2 different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking molindone, it is especially important that your health care professional know if you are taking any of the following:

• Amoxapine (e.g., Asendin) or
• Methyldopa (e.g., Aldomet) or
• Metoclopramide (e.g., Reglan) or
• Metyrosine (e.g., Demser) or
• Other antipsychotics (medicine for mental illness) or
• Pemoline (e.g., Cylert) or
• Pimozide (e.g., Orap) or
• Promethazine (e.g., Phenergan) or
• Rauwolfia alkaloids (alseroxylon [e.g., Rauwiloid], deserpidine [e.g., Harmonyl], rauwolfia serpentina [e.g., Raudixin], reserpine [e.g., Serpasil]) or
• Trimeprazine (e.g., Temaril) - Taking these medicines with molindone may increase the chance and seriousness of some side effects

• Central nervous system (CNS) depressants (medicine that causes drowsiness) or
• Tricyclic antidepressants (medicine for depression) - Taking these medicines with molindone may increase the CNS depressant effects

• Lithium (e.g., Eskalith, Lithane) - The chance of serious side effects may be increased

Other medical problems - The presence of other medical problems may affect the use of molindone. Make sure you tell your doctor if you have any other medical problems, especially:

• Brain tumor or
• Intestinal blockage - Molindone may interfere with the diagnosis of these conditions

• Difficult urination or
• Enlarged prostate or
• Glaucoma or
• Liver disease or
• Parkinson's disease - Molindone may make the condition worse