Nafarelin (Systemic)

Brand Names : Synarel

Side Effects of This Medicine

In the first few weeks of therapy, you may notice puberty progressing in your child, including vaginal bleeding and breast enlargement in girls. Within 4 weeks after nafarelin has had time to begin working properly, you should see signs in boys and girls that puberty is stopping. However, pubic hair may continue to show or grow in either boys or girls.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

For adults (female)

Breast enlargement; light vaginal bleeding between regular menstrual periods called spotting; longer or heavier menstrual periods; vaginal bleeding between regular menstrual periods called breakthrough bleeding

For children (male)

Body odor; growth of pubic hair

For children (female)

Body odor; breast enlargement; growth of pubic hair; light vaginal bleeding between regular menstrual periods called spotting; longer or heavier menstrual periods; vaginal bleeding between regular menstrual periods called breakthrough bleeding

Less common or rare

For adults (female)

Allergic reaction (shortness of breath, chest pain, hives); fast or irregular heartbeat; numbness or tingling of hands or feet; pain in eyes or joints; patchy brown or dark brown discoloration of skin; pelvic bloating or tenderness; unexpected or excess milk flow from breasts; unusual tiredness or weakness

For children (male and female)

Allergic reaction (shortness of breath, chest pain, hives)

Other side effects may occur that usually do not need medical attention. Some of these side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

For adults (female)

Acne; dandruff; hot flashes; increase or decrease in sexual desire; increased hair growth, often abnormally distributed; mood swings; muscle pain; oily skin; pain during sexual intercourse; rapid weight gain; reduced breast size; stopping of menstrual periods; swelling of feet or lower legs; vaginal dryness

For children (male)

Acne; dandruff; mood swings; oily skin

For children (female)

Acne; dandruff; hot flashes; mood swings; oily skin

Less common or rare

For adults (female)

Breast pain; headache (mild and transient); irritated or runny nose; mental depression (mild and transient); skin rash

For children (male)

Irritated or runny nose

For children (female)

Irritated or runny nose; white or brownish vaginal discharge

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.