Orphenadrine (Systemic)

Brand Names : Antiflex, Banflex, Flexoject, Mio-Rel, Myolin, Myotrol, Norflex, Orfro, Orphenate, Disipal

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For orphenadrine, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to orphenadrine. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy - Orphenadrine has not been reported to cause birth defects or other problems in humans.

Breast-feeding - It is not known whether orphenadrine passes into the breast milk. However, orphenadrine has not been reported to cause problems in nursing babies.

Children - Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of orphenadrine in children with use in other age groups.

Older adults - Many medicines have not been tested in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information about the use of orphenadrine in the elderly.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking orphenadrine, it is especially important that your health care professional knows if you are taking any of the following:

• Alcohol or
• Central nervous system (CNS) depressants or
• Tricyclic antidepressants (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil]) - The chance of side effects may be increased

Other medical problems - The presence of other medical problems may affect the use of orphenadrine. Make sure you tell your doctor if you have any other medical problems, especially:

• Disease of the digestive tract, especially esophagus disease, stomach ulcer, or intestinal blockage, or
• Enlarged prostate or
• Fast or irregular heartbeat or
• Glaucoma or
• Myasthenia gravis or
• Urinary tract blockage - Orphenadrine has side effects that may be harmful to people with these conditions

• Heart disease or
• Kidney disease or
• Liver disease - The chance of side effects may be increased