Penicillins and Beta-Lactamase Inhibitors (Systemic)

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Stop taking this medicine and get emergency help immediately if any of the following side effects occur:

Less common

Cough; fast or irregular breathing; fever; joint pain; lightheadedness or fainting (sudden); pain, redness, or swelling at site of injection; puffiness or swelling around the face; red, irritated eyes ; shortness of breath; skin rash, hives, itching; sore mouth or tongue; unusual tiredness or weakness; vaginal itching and discharge; white patches in mouth and/or on tongue

In addition to the side effects mentioned above, check with your doctor immediately if any of the following side effects occur:

Rare

Abdominal or stomach cramps and pain (severe); blistering, peeling, or loosening of skin and mucous membranes; chest pain; cloudy urine; convulsions (seizures); diarrhea (watery and severe), which may also be bloody; general feeling of illness or discomfort; nausea or vomiting; redness, soreness, or swelling of tongue; red skin lesions, often with a purple center; sore throat; swelling of face, fingers, lower legs, or feet; trouble in urinating; unusual bleeding or bruising; weight gain; yellow eyes or skin

Note:

Some of the above side effects (severe abdominal or stomach cramps and pain, and watery and severe diarrhea, which may also be bloody) may also occur up to several weeks after you stop taking any of these medicines.

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Diarrhea (mild); gas; headache; stomach pain; swelling of abdomen

Less common or rare

Chills; nosebleed; long-lasting muscle relaxation (with piperacillin and tazobactam combination); unusual tiredness or weakness

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.