Probenecid and Colchicine (Systemic)

Brand Names : ColBenemid, Col-Probenecid, Proben-C

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

The following side effects may mean that you are having an allergic reaction to this medicine. Check with your doctor immediately if any of the following side effects occur:

Rare

Fast or irregular breathing; puffiness or swelling of the eyelids or around the eyes; shortness of breath, troubled breathing, tightness in chest, or wheezing; changes in the skin color of the face occurring together with any of the other side effects listed here; or skin rash, hives, or itching occurring together with any of the other side effects listed here

Also check with your doctor immediately if any of the following side effects occur:

Symptoms of overdose

Bloody urine; burning feeling in stomach, throat, or skin; convulsions (seizures); diarrhea (severe or bloody); fever; mood or mental changes; muscle weakness (severe); nausea or vomiting (severe and continuing); sudden decrease in amount of urine; troubled or difficult breathing

Also, check with your doctor as soon as possible if any of the following side effects occur:

Less common

Difficult or painful urination; lower back or side pain (especially if severe or sharp); skin rash, hives, or itching (occurring without other signs of an allergic reaction)

Rare

Black or tarry stools; cloudy urine; cough or hoarseness; fast or irregular breathing; numbness, tingling, pain, or weakness in hands or feet; pinpoint red spots on skin; sores, ulcers, or white spots on lips or in mouth; sore throat, fever, and chills; sudden decrease in the amount of urine; swelling of face, fingers, feet, and/or lower legs; swollen and/or painful glands; unusual bleeding or bruising; unusual tiredness or weakness; yellow eyes or skin; weight gain

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Diarrhea (mild); headache; loss of appetite; nausea or vomiting (mild); stomach pain

Less common

Dizziness; flushing or redness of face (occurring without any signs of an allergic reaction); frequent urge to urinate; sore gums; unusual loss of hair

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.