Reserpine, Hydralazine, and Hydrochlorothiazide (Systemic)

Brand Names : Cam-Ap-Es, Cherapas, Ser-A-Gen, Seralazide, Ser-Ap-Es, Serpazide, Tri-Hydroserpine, Unipres

Side Effects of This Medicine

Suggestions that rauwolfia alkaloids may increase the risk of breast cancer occurring later have not been proven. However, rats and mice given 100 to 300 times the human dose had an increased number of tumors.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

General feeling of discomfort or illness or weakness

Less common

Drowsiness or faintness; impotence or decreased sexual interest; lack of energy or weakness; mental depression or inability to concentrate; nervousness or anxiety; vivid dreams or nightmares or early-morning sleeplessness

Check with your doctor as soon as possible if any of the following side effects occur:

Signs and symptoms of too much potassium loss

Dryness of mouth; increased thirst; irregular heartbeat; mood or mental changes; muscle cramps or pain; weak pulse

Signs and symptoms of too much sodium loss

Confusion; convulsions; decreased mental activity; irritability; muscle cramps; unusual tiredness or weakness

Less common

Black, tarry stools; blisters on skin; bloody vomit; chest pain; fever and sore throat; headache; irregular heartbeat; joint pain; numbness, tingling, pain, or weakness in hands or feet; shortness of breath; skin rash or itching; slow heartbeat; stomach cramps or pain; swelling of lymph glands

Rare

Lower back or side pain; painful or difficult urination; stiffness; stomach pain (severe) with nausea and vomiting; trembling and shaking of hands and fingers; unusual bleeding or bruising; yellow eyes or skin

Signs and symptoms of overdose

Dizziness or drowsiness (severe); dryness of mouth; flushing of skin; increased thirst; muscle cramps or pain; nausea or vomiting (severe); pinpoint pupils of eyes; slow pulse

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Diarrhea; dizziness, especially when getting up from a lying or sitting position; loss of appetite; nausea or vomiting; stuffy nose

Less common

Constipation; flushing or redness of skin; increased sensitivity of skin to sunlight; swelling of feet and lower legs; watering or irritated eyes

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time check with your doctor immediately if you notice any of the following side effects:

Drowsiness or faintness; general feeling of discomfort or illness or weakness; impotence or decreased sexual interest; irregular heartbeat; mental depression or inability to concentrate; nervousness or anxiety; vivid dreams or nightmares or early-morning sleeplessness

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.