Rimantadine (Systemic)

Brand Names : Flumadine

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For rimantadine, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to rimantadine or amantadine. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy - Studies have not been done in humans. However, studies in some animals have shown that rimantadine is harmful to the fetus and causes birth defects.

Breast-feeding - It is not known if rimantadine passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor.

Children - This medicine has been tested in children over one year of age and has not been shown to cause different side effects or problems in these children than it does in adults. There is no specific information comparing the use of rimantadine in children under one year of age with use in other age groups.

Older adults - Elderly people are especially sensitive to the effects of rimantadine. Difficulty in sleeping, difficulty in concentrating, dizziness, headache, nervousness, and weakness may be especially likely to occur. Stomach pain, nausea, vomiting, and loss of appetite may also occur.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other medical problems - The presence of other medical problems may affect the use of rimantadine. Make sure you tell your doctor if you have any other medical problems, especially:

• Epilepsy or other seizures (history of) - Rimantadine may increase the frequency of convulsions (seizures) in patients with a seizure disorder

• Kidney disease - Rimantadine is removed from the body by the kidneys; patients with severe kidney disease will need to receive a lower dose of rimantadine

• Liver disease - Patients with severe liver disease may need to receive a lower dose of rimantadine