Sirolimus (Systemic)

Brand Names : rapamycin, Rapamune

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Also, because of the way sirolimus acts on the body, there is a chance that it may cause effects that may not occur until years after the medicine is used. These delayed effects may include certain types of cancer, such as lymphoma.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Chest pain

black, tarry stools; general feeling of illness; shortness of breath; swollen glands; weight loss, unusual; yellow skin and eyes

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Abdominal pain; anxiousness, unexplained; bloody or cloudy urine; bone pain; chills; confusion; convulsions (seizures); cough; decreased urge to urinate; fast, slow, or irregular heartbeat; fever; frequent urge to urinate; increased thirst; loss of appetite; lower back or side pain; mood changes; muscle pain or cramps; nausea or vomiting; numbness or tingling around lips, hands, or feet; painful or difficult urination; rash; sore throat; sores or white spots on lips or in mouth; swelling of hands, ankles, feet, or lower legs; swollen glands; trouble breathing; unusual bleeding or bruising; unusual tiredness or weakness; weakness or heaviness of legs

Less common

Skin ulcer or sores

Rare

Weight gain, unusual

Unknown frequency

Abnormal wound healing

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Acne; constipation; diarrhea; difficulty in moving; headache; loss of energy or weakness; muscle pain or stiffness; pain; shaking or trembling; trouble in sleeping

Less common

Nosebleed; swelling of the face

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.