Sulfonamides and Trimethoprim (Systemic)

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Itching; skin rash

Less common

Aching of joints and muscles; difficulty in swallowing; pale skin; redness, blistering, peeling, or loosening of skin; sore throat and fever; unusual bleeding or bruising; unusual tiredness or weakness; yellow eyes or skin

Rare

Abdominal or stomach cramps and pain (severe); abdominal or stomach tenderness; anxiety; blood in urine; bluish fingernails, lips, or skin; confusion; diarrhea (watery and severe), which may also be bloody; difficult breathing; drowsiness; fever; general feeling of illness; greatly increased or decreased frequency of urination or amount of urine; hallucinations; headache, severe; increased thirst; lower back pain; mental depression; muscle pain or weakness; nausea; nervousness; pain at site of injection; pain or burning while urinating; seizures (convulsions); stiff neck and/or back; swelling of front part of neck

Note:

Some of the above side effects (severe abdominal or stomach cramps and pain, and watery and severe diarrhea, which may also be bloody) may also occur up to several weeks after you stop using any of these medicines.

Also, check with your doctor as soon as possible if the following side effect occurs:

More common

Increased sensitivity of skin to sunlight

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Diarrhea; dizziness; headache; loss of appetite; mouth sores or swelling of the tongue; nausea or vomiting; tiredness

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.