Tetracyclines (Systemic)

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. In some infants and children, tetracyclines may cause the teeth to become discolored. Even though this may not happen right away, check with your doctor as soon as possible if you notice this effect or if you have any questions about it.

For all tetracyclines

More common

Increased sensitivity of skin to sunlight (rare with minocycline)

Rare

Abdominal pain; bulging fontanel (soft spot on head) of infants; headache; loss of appetite; nausea and vomiting; visual changes; yellowing skin

For demeclocycline only

Less common

Greatly increased frequency of urination or amount of urine; increased thirst; unusual tiredness or weakness

For minocycline only

Less common

Pigmentation (darker color or discoloration) of skin and mucous membranes

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

For all tetracyclines

More common

Cramps or burning of the stomach; diarrhea

Less common

Itching of the rectal or genital (sex organ) areas; sore mouth or tongue

For minocycline only

More common

Dizziness, light-headedness, or unsteadiness

In some patients tetracyclines may cause the tongue to become darkened or discolored. This effect is only temporary and will go away when you stop taking this medicine.

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.