Trimethobenzamide (Systemic)

Brand Names : Benzacot, Stemetic, Tebamide, Tigan, Tribenzagan, Trimazide

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For trimethobenzamide, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to trimethobenzamide, or if you are allergic or sensitive to benzocaine or other local anesthetics (the suppository form of this medicine contains benzocaine). Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy - Studies have not been done in pregnant women. However, although studies in animals have not shown that trimethobenzamide causes birth defects, it has been shown to increase the chance of a miscarriage.

Breast-feeding - It is not known whether trimethobenzamide passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor.

Children - This medicine should not be used to treat nausea and vomiting in children unless otherwise directed by your doctor. Some side effects may be more serious in children.

Older adults - Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of trimethobenzamide in the elderly with use in other age groups.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are using trimethobenzamide, it is especially important that your health care professional know if you are taking any of the following:

• Central nervous system (CNS) depressants (medicine that causes drowsiness) or
• Tricyclic antidepressants (medicine for depression) - Taking these medicines with trimethobenzamide may cause increased CNS depressant or other serious effects

Other medical problems - The presence of other medical problems may affect the use of trimethobenzamide. Make sure you tell your doctor if you have any other medical problems, especially:

• High fever or
• Intestinal infection - Using trimethobenzamide may result in serious side effects