Trovafloxacin (Systemic)

Brand Names : Trovan, Alatrofloxacin, Trovafloxacin

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For alatrofloxacin or trovafloxacin, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to alatrofloxacin, trovafloxacin, any of the fluoroquinolones, or any related medicines, such as cinoxacin (e.g., Cinobac) or nalidixic acid (e.g., NegGram). Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy - Studies have not been done in humans. However, use is not recommended during pregnancy since alatrofloxacin and trovafloxacin have been reported to cause bone development problems in young animals.

Breast-feeding - Alatrofloxacin and trovafloxacin pass into breast milk. Since alatrofloxacin and trovafloxacin have been reported to cause bone development problems in young animals, breast-feeding is not recommended during treatment with either of these medicines.

Children - Use is not recommended for infants or children since alatrofloxacin and trovafloxacin have been shown to cause bone development problems in young animals.

Adolescents - Use is not recommended for teenagers up to 18 years of age since alatrofloxacin and trovafloxacin have been shown to cause bone development problems in young animals.

Older adults - Alatrofloxacin and trovafloxacin have been tested in and, in effective doses, have not been shown to cause different side effects or problems in older people than they do in younger adults.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking alatrofloxacin or trovafloxacin, it is especially important that your health care professional know if you are taking any of the following:

• Antacids that contain aluminum or magnesium or
• Citric acid buffered with sodium citrate (e.g., Bicitra) or
• Iron supplements or other vitamins or
• Morphine (injection dosage form) or
• Sucralfate - Antacids, citric acid buffered with sodium citrate, iron or vitamins, intravenous morphine, or sucralfate may keep trovafloxacin tablets from working properly

Other medical problems - The presence of other medical problems may affect the use of alatrofloxacin or trovafloxacin. Make sure you tell your doctor if you have any other medical problems, especially:

• Brain or spinal cord disease, including hardening of the arteries in the brain, or epilepsy or other problems that may cause seizures - Alatrofloxacin or trovafloxacin may cause nervous system side effects

• Liver disease - Patients with liver disease may have an increased chance of side effects