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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Atovaquone (Oral)

Atovaquone (By Mouth)

Atovaquone (a-TOE-va-kwone)

Treats Pneumocystis carinii pneumonia (PCP).

Brand Name(s):

Mepron
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to atovaquone.

How to Use This Medicine:

Tablet, Liquid

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • For the oral liquid, shake the bottle gently just before taking the medicine.
  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.
  • Take this medicine with a full meal. Atovaquone may not work as well if it is taken on an empty stomach, because less of the medicine will be absorbed into your body.
  • Tell your doctor if you cannot take this medicine with food.
  • Take this medicine on a regular schedule. Keep using the medicine for as long as your doctor has ordered, even if you are feeling better. If you stop the medicine too soon, your infection may come back.

If a dose is missed:

  • Take the missed dose as soon as possible, unless it is almost time for your next dose.
  • Skip the missed dose if it is almost time for your next regular dose.
  • You should not use two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store the medicine at room temperature away from heat and direct light. Do not freeze. Keep tightly closed.
  • Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also taking rifampin (Rifadin®, Rimactane®) or rifabutin (Mycobutin®). Atovaquone may not work as well if taken with either of these two medicines.
Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
  • Make sure your doctor knows if you have any stomach or bowel problems.
  • If you have human immunodeficiency virus (HIV) infection, atovaquone will not keep you from giving HIV or other infections to your partner during sex. Make sure you understand and practice safe sex, even if your partner also has HIV. Do not share needles with anyone else.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Fever
  • Rash or hives

If you notice these less serious side effects, talk with your doctor:

  • Nausea, upset stomach, vomiting
  • Trouble sleeping
  • Diarrhea
  • Headache
If you notice other side effects that you think are caused by this medicine, tell your doctor.


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