Dinoprostone (Vaginal) (Cervidil; Prepidil; Prostin E2) - Drugs Information, Side Effects, & Interactions

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Dinoprostone (dye-noe-PROST-one)

Helps dilate the opening of the uterus (cervix) in a pregnant woman. Belongs to a class of drugs called prostaglandins.

Cervidil, Prostin E2, Prepidil
There may be other brand names for this medicine.

You should not receive this medicine if you have had an allergic reaction to dinoprostone.

Insert, Suppository, Gel/Jelly

You will receive this medicine in a hospital or clinic, unless otherwise directed by your doctor.
A nurse or doctor will insert this medicine into your vagina so that the medicine comes into contact with your cervix. The nurse or doctor will need to use a speculum to insert the gel.
The gel or suppository should be brought to room temperature just before being placed in the vagina.
You will need to lie on your back for up to 2 hours after the insert is put in place. You will need to lie on your back for up to 30 minutes after the gel or suppository is inserted.
The insert will be removed 12 hours after it was inserted or when active labor begins.

If you use this medicine at home, store the insert or suppository in a freezer, away from heat and light until you are ready to insert it.
Keep all medicine out of the reach of children.

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Tell your doctor if you have had any unusual vaginal bleeding, if you have had 6 or more full-term pregnancies, or if you have pelvic inflammatory disease.
Let your doctor know if you have heart disease, liver disease, kidney problems, asthma, lung disease, or a history of bleeding disorders, diabetes, glaucoma, or seizures.
If you are breastfeeding, talk to your doctor before using this medicine.

Call your doctor right away if you notice any of these side effects:

If you notice these less serious side effects, talk with your doctor:

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