Hydrochlorothiazide (Oral) (Aquazide H; Hydrocot; Zide) - Drugs Information, Side Effects, & Interactions

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Hydrochlorothiazide (hye-droe-klor-oh-THYE-a-zide)

Treats high blood pressure and fluid retention (edema). This medicine is a diuretic (water pill).

Hydrocot, Zide, Aquazide H
There may be other brand names for this medicine.

You should not use this medicine if you have had an allergic reaction to hydrochlorothiazide or sulfa drugs, or if you are unable to urinate.

Tablet, Liquid

Your doctor will tell you how much of this medicine to take and how often. Do not take more medicine or take it more often than your doctor tells you to.
Carefully follow your doctor's instructions about any special diet. You may need to eat foods that are high in potassium (such as oranges or bananas) to prevent potassium loss while you are using this medicine.
Measure the oral liquid medicine with a marked measuring spoon or medicine cup.

If a dose is missed:

If you miss a dose or forget to take your medicine, take it as soon as you can. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose.
Do not use extra medicine to make up for a missed dose.

Store the medicine at room temperature, away from heat, moisture, and direct light. Do not freeze.
Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
Keep all medicine out of the reach of children and never share your medicine with anyone.

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Make sure your doctor knows if you are also using cholestyramine (Questran®), colestipol (Colestid®), digoxin (Lanoxin®), lithium, pain or arthritis medicine (such as aspirin, Advil®, Aleve®, Indocin®, Motrin®, Orudis®, Relafen®, Voltaren®), steroids (such as cortisone, prednisone), or low-salt milk.
Do not drink alcohol while you are using this medicine.

Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney or liver disease, gout, diabetes, or lupus.
This medicine may make you dizzy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
This medicine may make your skin more sensitive to sunlight. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.
Make sure any doctor or dentist who treats you knows that you are using this medicine.

Call your doctor right away if you notice any of these side effects:

Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
Blood in urine or stools
Confusion, weakness, irregular heartbeat, shortness of breath, numbness or tingling in hands, feet, or lips
Dry mouth, increased thirst, muscle cramps, nausea or vomiting
Fever chills, cough, hoarseness
Problems urinating, pain in side or lower back
Skin rash or itching
Unusual bleeding or bruising
Yellow eyes or skin

If you notice these less serious side effects, talk with your doctor:

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