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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Hydrocortisone (Topical)

Hydrocortisone (On The Skin)

Hydrocortisone (hye-droe-KOR-ti-sone)

Treats skin irritation, allergic reactions, and other types of skin problems. Belongs to a class of drugs called corticosteroids.

Brand Name(s):

Locoid, Locoid Lipocream, Hytone, Pandel, Caldecort, Caldecort Light, Medi-Cortisone Maximum Strength, Nupercainal Hc 1%, Cortaid Sensitive Skin w/Aloe, Foille Cort, Cortaid Maximum Strength, Westcort, Cotacort, Microcort, Lacticare-HC
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to hydrocortisone or any other related medicine, such as triamcinolone (Aristocort®), betamethasone (Valisone®), or fluocinonide (Lidex®).

How to Use This Medicine:

Cream, Ointment, Lotion, Spray, Gel/Jelly, Stick, Liquid

  • Your doctor will tell you how much to use and how often.
  • This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.
  • Use only on the skin. You should not use this medicine in or around your eyes.
  • You should not use this medicine on your face or neck unless your doctor told you to do so.
  • Apply a thin layer to the affected area. Rub in gently.
  • Shake the lotion well before using.
  • The spray could catch on fire. Do not use the spray near high heat or flame.
  • Do not cover the treated skin with a bandage unless your doctor tells you to do so.
  • If this medicine is used on the diaper area of a child, avoid using tight-fitting diapers or plastic pants.

If a dose is missed:

  • Put on the missed dose as soon as possible.
  • Skip the missed dose if it is almost time for your next regular dose.
  • You should not use two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store at room temperature, away from heat, moisture, and direct light. Do not freeze.
  • Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Do not mix with or use other skin medicines with this medicine unless your doctor tells you to do so.
Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk to your doctor before using hydrocortisone.
  • Make sure your doctor knows if you have glaucoma, tuberculosis, diabetes, chickenpox, or a skin infection.
  • You should not use this medicine for other skin conditions without first checking with your doctor or pharmacist.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Severe itching, burning, or skin irritation
  • Redness, swelling, drainage, or pus from the area or other signs of infection

If you notice these less serious side effects, talk with your doctor:

  • Mild, temporary stinging
  • Irritation, burning, redness, or dryness of skin
  • Raised spots on skin
  • Thinning of skin or bruising
  • Poor healing of skin
  • Acne-like skin changes
If you notice other side effects that you think are caused by this medicine, tell your doctor.


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