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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Hydromorphone (Oral)

Hydromorphone (By Mouth)

Hydromorphone (hye-droe-MOR-fone)

Treats pain and severe cough. Belongs to a class of drugs called narcotic analgesics.

Brand Name(s):

Dilaudid, Dilaudid-5
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to hydromorphone or related drugs such as codeine, morphine, or hydrocodone (Tussionex®).

How to Use This Medicine:

Tablet, Liquid

  • Your doctor will tell you how much to take and how often.
  • May be taken with food to lessen stomach upset.
  • Store at room temperature, away from heat and moisture.
  • Measure the oral liquid carefully using a measuring spoon or medicine cup.

If a dose is missed:

  • Take the missed dose as soon as possible.
  • If it is almost time for your next dose, wait until then to take your medicine and skip the missed dose.
  • You should not use two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store at room temperature, away from heat and moisture.
  • Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Avoid drinking alcohol.
  • Make sure your doctor knows if you are taking any other kind of medicine that could make you sleepy, such as sedatives, sleeping pills, or muscle relaxants.
Warnings While Using This Medicine:

  • Check with your doctor before taking hydromorphone if you have asthma, stomach or intestinal problems, or lung disease.
  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
  • This medicine can be habit-forming. You should not use more than your doctor ordered.
  • If you have taken this medicine for several weeks, do not suddenly stop taking it You may need to take smaller and smaller doses before stopping completely.
  • This medicine may cause dizziness or confusion. Be careful if driving a car or using machinery.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Rapid or slowed heartbeat
  • Trouble breathing
  • Hives, skin rash, or itching
  • Severe confusion or tiredness
  • Tremors
  • Trouble going to the bathroom (urinating)

If you notice these less serious side effects, talk with your doctor:

  • Drowsiness, dizziness, or weakness
  • Dry mouth, nausea, or vomiting
  • Constipation
  • Nervousness
If you notice other side effects that you think are caused by this medicine, tell your doctor.


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