Imipenem/Cilastatin (Injection) (Primaxin IM; Primaxin IV) - Drugs Information, Side Effects, & Interactions

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Cilastatin (sye-la-STAT-in), Imipenem (i-mi-PEN-em)

Treats infections caused by bacteria. Belongs to a class of drugs called antibiotics.

Primaxin IV, Primaxin IM
There may be other brand names for this medicine.

You should not receive this medicine if you have had an allergic reaction to imipenem, cilastatin, or medicine that causes numbing such as lidocaine.

Injectable

Your doctor will prescribe your exact dose and tell you how often it should be given.
An intramuscular (in-tra-MUS-kyoo-ler) or IM injection is a shot given in the muscle of your thigh or buttocks.
An intravenous (in-tra-VEEN-us) or IV injection is given through a tube put in one of your veins, usually in your arm, wrist, hand, or sometimes in your chest.
A nurse or other caregiver trained to give injections will give your treatment.
Sometimes you, a family member, or friend can be taught to give your medicine at home.
If you have your treatments at home, you should be given a special container for the used needles. Keep it where children or pets cannot reach it.
Use a new needle and syringe each time you inject your medicine.

If a dose is missed:

Store the liquid medicine in a refrigerator. Do not freeze. Take it out of the refrigerator an hour before the time for your next dose and let it warm to room temperature in a clean, dry place.
Store the dry powder and bottles at room temperature, away from heat, moisture, and direct light.
Keep all medicine out of the reach of children.

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Make sure your doctor knows if you are taking probenecid (Benemid®) or ganciclovir (Cytovene®) before you are treated with imipenem/cilastatin.

Make sure your doctor knows if you have ever had an allergic reaction, especially to any other antibiotics such as penicillin or cephalosporin (Keflex®, Ceclor®).
If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
Make sure your doctor knows if you have kidney disease or a seizure disorder.
If this medicine gives you diarrhea, talk to your doctor before taking medicine to stop the diarrhea.
If your infection does not get better or if it gets worse while you are using this medicine, tell your doctor.

Call your doctor right away if you notice any of these side effects:

If you notice these less serious side effects, talk with your doctor:

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