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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Insulin Human Glargine (Injection)

Insulin Human Glargine (Injection)

Insulin Glargine, Recombinant (IN-su-lin GLAR-jeen, re-KOM-bi-nant)

Treats diabetes mellitus (sugar diabetes). This is a long-acting insulin.

Brand Name(s):

Lantus
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

Talk with your doctor before using this medicine if you have had an allergic reaction to any type of insulin.

How to Use This Medicine:

Injectable

  • Your doctor will tell you how much of this medicine to use and how often. Do not change the brand or dose of your insulin unless your doctor tells you to. When you receive a new supply of insulin, check the labels to be sure you have received the correct type of insulin.
  • A doctor, nurse, or pharmacist should teach you how to give your insulin shots. Make sure you understand how to use the medicine and give yourself the shots.
  • A subcutaneous (sub-kyoo-TANE-ee-us) or SC injection is a shot given just under your skin, usually on the back of your arm or the top of your thigh, or on your stomach.
  • Use a different area to give your shot each time you use your medicine. Keeping a record of where you give each injection will help make sure you rotate areas.
  • If you are using a vial (bottle) of Lantus®, use only syringes that are specially made for giving insulin injections, and use a new syringe each time you give yourself insulin. If you are using a cartridge of Lantus®, use a new needle each time.
  • Do not dilute Lantus® or mix it with any other insulin or solution.

If a dose is missed:

  • Ask your doctor what to do if you miss a dose of insulin.
How to Store and Dispose of This Medicine:

  • Lantus® should look clear and colorless. Do not use this insulin if it looks cloudy, discolored, or has particles in it.
  • Store unused bottles and cartridges in the refrigerator. Do not freeze. The expiration date on the insulin package tells you how long you can keep the medicine in the refrigerator. Throw the medicine away after the expiration date has passed.
  • If you are using a bottle of Lantus® and cannot refrigerate it, the bottle you are currently using may be kept at room temperature in a cool place, away from direct light and heat. A 10 milliliter (mL) bottle may be kept unrefrigerated for 28 days. A 5 milliliter (mL) bottle may be kept unrefrigerated for 14 days.
  • If you are using a cartridge of Lantus® and cannot refrigerate it, the cartridge may be kept at room temperature in a cool place, away from direct light and heat, for 28 days.
  • Once a cartridge of Lantus® is placed into the OptiPen™ One Insulin Delivery Device, it should not be put in the refrigerator.
  • You should receive a container for throwing away your used needles and syringes. Otherwise, throw your used needles away in a hard, closed container that the needles cannot poke through. Keep this container out of the reach of children and pets.
  • Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can make it harder for you to control your diabetes. Make sure your doctor knows about all other medicines you are using.
Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.
  • Follow the special diet and use the correct dose of insulin that your doctor orders. Your health caregiver can also help you start an exercise program. You may also have to learn to check your own blood sugar. If you have questions about how to check your blood sugar, ask your doctor or nurse. Diet, exercise, medicine, and checking your blood sugar are important to control your diabetes.
  • You may have low blood sugar while you are using insulin, especially if you miss a meal, exercise for a long time, or drink alcohol.
  • If your blood sugar gets too low, you may feel shaky, weak, drowsy, cold, confused, or very hungry. You may sweat or have blurred vision, a fast heartbeat, trouble concentrating, or a headache that doesn't go away.
  • Ask your doctor what to do if you have low blood sugar. You will need to control it quickly. Teach your friends, co-workers, or family members what they can do to help you in case you have low blood sugar.
  • Make sure your doctor knows if you have kidney or liver disease.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
  • Fainting
  • Seizures (convulsions)

If you notice these less serious side effects, talk with your doctor:

  • Pain at place where shot is given
  • Redness, itching, or swelling where the shot is given
If you notice other side effects that you think are caused by this medicine, tell your doctor.


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