Lansoprazole/Amoxicillin/Clarithromycin (By Mouth)

Treats a stomach infection (H pylori) that causes ulcers. This medicine is a combination of an antacid and two different antibiotics.

Brand Name(s):

Prevpac
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to lansoprazole, amoxicillin, or clarithromycin, or to any other penicillin or macrolide antibiotic (such as azithromycin, erythromycin, Zithromax®, Biaxin®). You should not use this medicine if you are also using cisapride (Propulsid®), pimozide (Orap®), or terfenadine (Seldane®).

How to Use This Medicine:

Capsule, Tablet, Delayed Release Capsule

• Your doctor will tell you how much of this medicine to take and how often. Do not take more medicine or take it more often than your doctor tells you to. It is important that you take all three medicines as directed.
• Swallow the capsules and tablets whole. Do not chew, crush, or break any of them.
• It is best to take this medicine on an empty stomach, before a meal.
• Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

If a dose is missed:

• If you miss a dose or forget to take your medicine, take it as soon as you can. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose.
• Do not use extra medicine to make up for a missed dose.

How to Store and Dispose of This Medicine:

• Store the medicine at room temperature, away from heat, moisture, and direct light.
• Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
• Keep all medicine away from children and never share your medicine with anyone.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

• Make sure your doctor knows if you are also using theophylline, ketoconazole (Nizoral®), ampicillin, iron, digoxin (Lanoxin®), carbamazepine (Tegretol®), triazolam (Halcion®), astemizole (Hismanal®), a blood thinner such as warfarin (Coumadin®), medicines to treat HIV/AIDS (Agenerase®, Crixivan®, Invirase®, Norvir®, Retrovir®, Sustiva®, Viracept®), ergot medicines (such as Cafergot® or Wigraine®), or medicine to lower cholesterol (such as Lescol®, Lipitor®, Mevacor®, Pravachol®, Zocor®).
• If you are also taking sucralfate (Carafate®), you should take the medicines in Prevpac® at least 30 minutes before taking sucralfate.

Warnings While Using This Medicine:

• Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease or diabetes. Tell your doctor if you are allergic to cephalosporin antibiotics (such as cefaclor, cefadroxil, cephalexin, Ceftin®, Keflex®) or any other medicines.
• If you have severe diarrhea, ask your doctor before taking any medicine to stop the diarrhea.
• If your symptoms do not improve or if they get worse, call your doctor.
• Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
• Blistering, peeling, red skin rash
• Diarrhea (may be watery or contain blood)
• Fast or irregular heartbeat
• Nausea, vomiting, loss of appetite, pain in your upper stomach
• Yellow skin or eyes, dark-colored urine or pale stools

If you notice these less serious side effects, talk with your doctor:

• Bad taste in your mouth
• Change in the color of your teeth or tongue
• Headache
• Nausea
• Vaginal itching or discharge

If you notice other side effects that you think are caused by this medicine, tell your doctor.