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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Nystatin (Oral)

Nystatin (By Mouth)

Nystatin (nye-STA-tin)

Treats fungus infections in the mouth, throat, and intestines. Belongs to a class of drugs called antifungals.

Brand Name(s):

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to nystatin.

How to Use This Medicine:

Lozenge, Liquid, Powder for Suspension, Tablet

  • Your doctor will tell you how much medicine to use and how often. Use the medicine for as long as your doctor told you to, even if your symptoms are gone.
  • Shake the oral liquid well just before each dose. Measure your dose with the dropper that comes with the medicine. Keep the medicine in your mouth for as long as possible. Swish it around, gargle, and swallow.
  • Add 1/8 teaspoonful of the dry powder to 1/2 cup of water. Stir well. Keep this mixture in your mouth for as long as possible. Swish it around, gargle, and swallow.
  • Swallow the tablet whole. Do not crush or chew.
  • Let the lozenge melt slowly in your mouth. Do not chew or swallow it whole.
  • Do not give the lozenge to infants or children younger than 5 years old.

If a dose is missed:

  • Use the missed dose as soon as possible.
  • If it is almost time for your next regular dose, wait until then to use your medicine and skip the missed dose.
  • You should not use two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store the lozenges or powder in the refrigerator.
  • Store the oral liquid or tablets at room temperature in a tightly closed container away from heat, direct light, and moisture. Do not freeze.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:


Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.


Warnings While Using This Medicine:

  • If you are pregnant or breastfeeding, talk with your doctor before using nystatin.
Possible Side Effects While Using This Medicine:

If you notice these less serious side effects, talk with your doctor:

  • Diarrhea
  • Nausea
  • Mild stomach upset
If you notice other side effects that you think are caused by this medicine, tell your doctor.


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