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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Penicillin V (Oral)

Penicillin V (By Mouth)

Penicillin V (pen-i-SILL-in V)

Treats infections.

Brand Name(s):

Veetids, Truxcillin VK
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have had an allergic reaction to any type of penicillin.

How to Use This Medicine:

Tablet, Liquid

  • Your doctor will tell you how much of this medicine to take and how often. Do not take more medicine or take it more often than your doctor tells you to.
  • It is best to take this medicine on an empty stomach, 1 hour before or 2 hours after a meal.
  • Shake the oral liquid well just before each use. Measure the medicine with a marked measuring spoon or medicine cup.
  • Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

If a dose is missed:

  • If you miss a dose or forget to take your medicine, take it as soon as you can. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose.
  • Do not use extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:

  • Store the tablets at room temperature, away from heat, moisture, and direct light.
  • Store the oral liquid in the refrigerator. Do not freeze.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine out of the reach of children and never share your medicine with anyone.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using probenecid (Benemid®).
  • Birth control pills, implants, or shots may not work while you are using penicillin. To keep from getting pregnant, use another form of birth control such as condoms, a diaphragm, or contraceptive foam or jelly.
Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have asthma, allergies, kidney disease, or liver disease. Tell your doctor if you have ever had an allergic reaction to a cephalosporin antibiotic (such as cefaclor, cefadroxil, cephalexin, Ceftin®, Keflex®).
  • If you have severe diarrhea, ask your doctor before taking any medicine to stop the diarrhea.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
  • Blistering, peeling, red skin rash
  • Diarrhea (may be watery or contain blood)

If you notice these less serious side effects, talk with your doctor:

  • Nausea or upset stomach
  • Vaginal itching or discharge
If you notice other side effects that you think are caused by this medicine, tell your doctor.


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