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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Pseudoephedrine (Oral)

Pseudoephedrine (By Mouth)

Pseudoephedrine (soo-doe-e-FED-rin)

Treats nasal and sinus stuffiness from the common cold, hay fever, and sinusitis. Belongs to a class of drugs called decongestants.

Brand Name(s):

Sudafed, Sudafed 12 Hour, Simply Stuffy, Pseudo-Gest, Cenafed, Pseudocot, Sudanyl, Sudodrin, Sudodrine, Sudo-Tab, Kodet Se, Genaphed, Ridafed, Contac 12-Hour, 12 Hour Cold Maximum Strength
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to pseudoephedrine.

How to Use This Medicine:

Long Acting Capsule, Long Acting Tablet, Tablet

  • Your doctor will tell you how much medicine to take and how often.
  • Read label directions carefully. Avoid taking at bedtime; this medicine may make you restless.
  • Swallow the capsule or tablet whole. Do not crush, chew, or break.

If a dose is missed:

  • Take your medicine as soon as you remember that you have missed your dose.
  • If it has been more than 1 hour since the time you were scheduled to take your medicine, wait until your next dose and skip the missed dose.
  • You should not use two doses at one time.
How to Store and Dispose of This Medicine:

  • Keep your medicine at room temperature, away from heat, light, and moisture. Do not freeze.
  • Keep all medicine away from children.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • You should not use pseudoephedrine with cocaine, monoamine oxidase (MAO) inhibitors (Parnate®, Marplan®, Eldepryl®).
Warnings While Using This Medicine:

  • Check with your doctor before taking if you are pregnant or breastfeeding, or if you have heart disease, high blood pressure, diabetes, trouble urinating due to an enlarged prostate, or an overactive thyroid.
  • You should not use this medicine for more than 7 days unless ordered by a doctor.
  • If you do not get better after taking this medicine for 7 days, or if you have a fever, talk to your doctor.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Chest pain
  • Very fast, pounding, or irregular heartbeat
  • Wheezing or shortness of breath
  • Convulsions (seizures)
  • Severe restlessness
  • Hallucinations

If you notice these less serious side effects, talk with your doctor:

  • Nervousness or dizziness
  • Trouble sleeping
  • Nausea or upset stomach
  • Headache
If you notice other side effects that you think are caused by this medicine, tell your doctor.


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