Thioguanine (Oral) - Drugs Information, Side Effects, & Interactions

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Thioguanine (thye-oh-GWAH-neen)

Used with other medicines to treat different kinds of leukemia.

There may be other brand names for this medicine.

You should not use this medicine if you have ever had an allergic reaction to thioguanine or mercaptopurine (Purinethol®).

Tablet

This medicine, like all medicines used to treat cancer, is very strong. Make sure you understand why you are getting it and what the risks and benefits of treatment are. It is important for you to work closely with your doctor.
Your doctor will tell you how much medicine to use and how often. Make sure you understand your doctor's instructions.
Drink at least 6 to 8 large glasses of liquid every day while you are using this medicine.
If you vomit right after you take this medicine, call your doctor.

If a dose is missed:

Take the medicine as soon as possible, unless it is almost time for your next dose.
Skip the missed dose if it is almost time for your next regular dose.
You should not use two doses at the same time.

Store at room temperature in the original container, away from heat, moisture, and light. Keep the container closed tightly.
Keep all medicine out of the reach of children.

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

Avoid drinking alcohol while using thioguanine.
You should not use aspirin or any product that has aspirin in it (such as some cold medicines) unless you have talked to your doctor.
Talk to your doctor before having any vaccines (such as a flu shot).

If you are pregnant, talk to your doctor before you start your treatments.
Do not breastfeed while you are being treated with this medicine.
Do not get pregnant while you or your sexual partner are receiving thioguanine. Use an effective form of birth control while you are being treated with this medicine.
Tell your doctor if you have gout, liver disease, or a history of kidney stones.
Your doctor may want you to have blood tests on a regular schedule while you are using this medicine. Keep all of your appointments, or reschedule any appointments you miss.
You may get infections more easily while using this medicine. Stay away from crowds and people with colds, flu, or other infections.
This medicine may make your mouth sore and irritated. Use a soft-bristle toothbrush or mouth swab to brush your teeth.

Call your doctor right away if you notice any of these side effects:

If you notice these less serious side effects, talk with your doctor:

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