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Histiocytosis
Alternate Names : Pulmonary Histiocytosis X, Histiocytosis X, Eosinophilic Granuloma, Nonlipid Reticuloendotheliosis, Langerhans Histiocytoses, Letterer-Siwe Disease, Hand-Schuller-Christian Disease, Pulmonary Langerhans' Granulomatosis
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How is the condition diagnosed?
In adults, the diagnosis of histiocytosis is made by:
chest x-ray
bronchoscopy, in which a small sample of the airways are removed and the airways are examined through a small scope
pulmonary function tests, a group of tests that measure the lungs' capacity to hold air, move air in and out, and exchange oxygen and carbon dioxide
In children the diagnosis is made by:
bone x-rays that show the "punched-out" appearance of bone lesions
x-rays of the entire body, to determine how much bone is involved
biopsies, or small samples, taken from the bone, bone marrow, and skin
blood tests
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Author: James Broomfield, MD Reviewer: Gail Hendrickson, RN, BS Date Reviewed: 07/02/01
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