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Aplastic Anemia
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Aplastic anemia is a condition in which the bone marrow fails to produce blood cells.
What is going on in the body?
The bone marrow contains special cells known as stem cells. Stem cells are like infant cells. They may develop into red blood cells, white blood cells, and platelets. Red blood cells carry oxygen throughout the body. White blood cells fight infection. Platelets control bleeding by forming blood clots in certain situations. Blood cells have a limited life, so new ones are made constantly. Certain conditions can damage stem cells or change their environment. The stem cells stop making blood cells. The bone marrow fills up with fat, instead of developing blood cells. The low level of red blood cells, white blood cells, and platelets in the body is known as aplastic anemia.
What are the causes and risks of the condition?
In 50% of the people with aplastic anemia, the cause is unknown. In other cases, the anemia may be caused by one of the following factors:
airplane glue
blood disorders
chemicals, such as benzene and pesticides
chemotherapy
drugs, such as chloramphenicol
inherited or genetic causes, which may be present at birth
pregnancy
radiation therapy
viruses such as herpes, hepatitis C, and HIV
Some experts believe that aplastic anemia is an autoimmune disorder, a condition in which the body produces antibodies against its own blood cells.
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Author: Thomas Fisher, MD Reviewer: Melissa Sanders, PharmD Date Reviewed: 05/14/01
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$alt_texts= array ('Benign prostatic hyperplasia, or BPH for short, is the enlargement of the prostate gland. It is caused by excess growth of cells in the prostate. This condition is not the same as prostate cancer','Alternate Names : Dysmenorrhea. Menstrual cramps are the pain and cramping some women experience during their monthly periods. The term dysmenorrhea usually refers to pain and cramps severe enough to prevent normal activity','An ectopic pregnancy occurs when a fertilized egg implants outside of the uterus. The most common site is within a fallopian tube. More rarely an embryo may implant within an ovary, in the cervix, or on the abdominal wall','Pregnancy is the period from conception to birth. A pregnancy may be complicated by health problems or lifestyle issues known as risk factors. These risk factors can affect the mother or fetus, or both','Topiramate (toe-PYRE-a-mate) is used to help control some types of seizures in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to help control seizures for as long as you continue to take it.','Irritable bowel syndrome, or IBS, is a condition characterized by abdominal cramping, bloating, gas, and other changes in the bowels','Depression is a medical condition that leads to intense feelings of sadness or despair. These feelings don\'t go away on their own. They are not necessarily related to a particular life event','Tacrolimus ( ta-KROE-li-mus) ointment is used for moderate to severe atopic dermatitis. This is a skin condition where there is itching, redness and inflammation, much like an allergic reaction','Type 2 diabetes mellitus, more often known as type 2 diabetes, is the most common type of diabetes','Personality disorders are chronic mental disorders','Presbyopia is an eye condition in which the lens loses the ability to focus over time');
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