Amlodipine and Benazepril (Systemic)
Brand Names : Lotrel
CategoryDescriptionAmlodipine (am-LOH-di-peen) and benazepril (ben-AY-ze-pril) combination belongs to the class of medicines called high
blood pressure medicines (antihypertensives). It is used to treat high blood
pressure (hypertension).
High blood pressure adds to the workload of the heart and arteries. If
it continues for a long time, the heart and arteries may not function properly.
This can damage the blood vessels of the brain, heart, and kidneys, resulting
in a stroke, heart failure, or kidney failure. High blood pressure may also
increase the risk of heart attacks. These problems may be less likely to occur
if blood pressure is controlled.
The exact way in which this medicine works is not known. Amlodipine is
a type of medicine known as a calcium channel blocker. Calcium channel blocking
agents affect the movement of calcium into the cells of the heart and blood
vessels. Benazepril is a type of medicine known as an angiotensin-converting
enzyme (ACE) inhibitor. It blocks an enzyme in the body that is necessary
in producing a substance that causes blood vessels to tighten. The action
of both medicines together is to relax blood vessels, lower blood pressure,
and increase the supply of blood and oxygen to the heart.
This medicine is available only with your doctor's prescription, in the
following dosage form:
Brand NamesSome commonly used brand names are:
In the U.S. -
† Not commercially available in Canada.
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