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Angiotensin-converting Enzyme (ACE) Inhibitors and Hydrochlorothiazide (Systemic)
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Category- Antihypertensive - Benazepril and Hydrochlorothiazide; Captopril and Hydrochlorothiazide; Enalapril
and Hydrochlorothiazide; Lisinopril and
Hydrochlorothiazide; Moexipril and Hydrochlorothiazide; Quinapril and Hydrochlorothiazide
- Vasodilator, congestive heart failure - Captopril and Hydrochlorothiazide; Enalapril
and Hydrochlorothiazide; Lisinopril and
Hydrochlorothiazide
DescriptionThis combination belongs to the class of medicines
called high blood pressure medicines (antihypertensives). It is used to treat
high blood pressure (hypertension).
High blood pressure adds to the workload of the heart and arteries. If
it continues for a long time, the heart and arteries may not function properly.
This can damage the blood vessels of the brain, heart, and kidneys, resulting
in a stroke, heart failure, or kidney failure. High blood pressure may also
increase the risk of heart attacks. These problems may be less likely to occur
if blood pressure is controlled.
The exact way in which benazepril, captopril, enalapril, lisinopril, moexipril,
and quinapril work is not known. They block an enzyme in the body that is
necessary to produce a substance that causes blood vessels to tighten. As
a result, they relax blood vessels. This lowers blood pressure and increases
the supply of blood and oxygen to the heart. Hydrochlorothiazide helps reduce
the amount of salt and water in the body by acting on the kidneys to increase
the flow of urine; this also helps to lower blood pressure.
This combination may also be used for other conditions as determined by
your doctor.
This medicine is available only with doctor's prescription, in the following
dosage forms:
Oral
-
Benazepril and Hydrochlorothiazide
-
Captopril and Hydrochlorothiazide
-
Enalapril and Hydrochlorothiazide
-
Tablets (U.S. and Canada)
-
Lisinopril and Hydrochlorothiazide
-
Tablets (U.S. and Canada)
-
Moexipril and Hydrochlorothiazide
-
Quinapril and Hydrochlorothiazide
-
Tablets (U.S. and Canada)
Brand NamesSome commonly used brand names are:
In the U.S. -
- Accuretic 6
- Capozide 2
- Lotensin HCT 1
- Prinzide 4
- Uniretic 5
- Vaseretic 3
- Zestoretic 4
In Canada -
- Accuretic 6
- Prinzide 4
- Vaseretic 3
- Zestoretic 4
Note:
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For quick reference, the following medicines are numbered to match
the corresponding brand names. |
This information applies to the following medicines: |
1. |
Benazepril and Hydrochlorothiazide (ben-AY-ze-pril and hye-droe-klor-oh-THYE-a-zide)† |
2. |
Captopril and Hydrochlorothiazide (KAP-toe-pril)†‡ |
3. |
Enalapriland Hydrochlorothiazide (e-NAL-a-pril) |
4. |
Lisinopril and Hydrochlorothiazide (lyse-IN-oh-pril) |
5. |
Moexipriland Hydrochlorothiazide (moe-EX-i-pril)† |
6. |
Quinapril and Hydrochlorothiazide (KWIN-a-pril) |
† Not commercially available in Canada |
‡ Generic name product may be available in the U.S. |
† Not commercially available in Canada.
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