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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Antihistamines, Phenothiazine-derivative

Antihistamines, Phenothiazine-derivative (Systemic)

Description and Brand Names | Before Using | Proper Use | Precautions | Side Effects

Category
  • Antiemetic - Promethazine
  • Antihistaminic, H 1 -receptor - Methdilazine; Promethazine; Trimeprazine
  • Antivertigo agent - Promethazine
  • Sedative-hypnotic - Promethazine; Trimeprazine
Description

Phenothiazine (FEE-noe-THYE-a-zeen)-derivative antihistamines are used to relieve or prevent the symptoms of hay fever and other types of allergy. They work by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. Also, in some persons histamine can close up the bronchial tubes (air passages of the lungs) and make breathing difficult.

Some of these antihistamines are also used to prevent motion sickness, nausea, vomiting, and dizziness. In addition, some of them may be used to help people go to sleep and control their anxiety before or after surgery.

Phenothiazine-derivative antihistamines may also be used for other conditions as determined by your doctor.

In the U.S. these antihistamines are available only with your doctor's prescription. In Canada some are available without a prescription. However, your doctor may have special instructions on the proper dose of the medicine for your medical condition.

These medicines are available in the following dosage forms:

    Oral
  • Methdilazine
    • Syrup (U.S.)
    • Tablets (U.S.)
    • Chewable tablets (U.S.)
  • Promethazine
    • Syrup (U.S. and Canada)
    • Tablets (U.S. and Canada)
  • Trimeprazine
    • Extended-release capsules (U.S.)
    • Syrup (U.S. and Canada)
    • Tablets (U.S. and Canada)
    Parenteral
  • Promethazine
    • Injection (U.S. and Canada)
    Rectal
  • Promethazine
    • Suppositories (U.S.)

Brand Names

Some commonly used brand names are:

In the U.S. -

  • Anergan 25 2
  • Anergan 50 2
  • Antinaus 50 2
  • Pentazine 2
  • Phenazine 25 2
  • Phenazine 50 2
  • Phencen-50 2
  • Phenergan 2
  • Phenergan Fortis 2
  • Phenergan Plain 2
  • Phenerzine 2
  • Phenoject-50 2
  • Pro-50 2
  • Promacot 2
  • Pro-Med 50 2
  • Promet 2
  • Prorex-25 2
  • Prorex-50 2
  • Prothazine 2
  • Prothazine Plain 2
  • Shogan 2
  • Tacaryl 1
  • Temaril 3
  • V-Gan-25 2
  • V-Gan-50 2

In Canada -

  • Histantil 2
  • Panectyl 3
  • Phenergan 2

Another commonly used name for trimeprazine is alimemazine .

Note:

For quick reference, the following antihistamines, are numbered to match the corresponding brand names.

This information applies to the following medicines:
1. Methdilazine (meth-DILL-a-zeen)†
2. Promethazine (proe-METH-a-zeen)‡§
3. Trimeprazine (trye-MEP-ra-zeen)‡
† Not commercially available in Canada
‡ Generic name product may be available in the U.S.
§ Generic name product may be available in Canada

   

Next section

   

Antihistamines, Phenothiazine-derivative: Before Using



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