Dornase Alfa (Inhalation)

Brand Names : Pulmozyme, rhDNase, DNase I

Category

• Cystic fibrosis therapy adjunct

Description

Dornase alfa (DOR-nayse AL-fa) is used in the management of cystic fibrosis. It is used every day with other cystic fibrosis medicines, especially antibiotics, bronchodilators (medicines that open up narrowed breathing passages), and corticosteroids (cortisone-like medicines).

Cystic fibrosis is a condition in which thick mucus is formed in the lungs and breathing passages. The mucus blocks the airways and increases the chance of lung infections. The infections then cause the mucus to become even thicker, making it more difficult to breathe.

Dornase alfa will not cure cystic fibrosis. However, when it is used every day, it helps make breathing easier and reduces the number of serious lung infections that require treatment with antibiotics.

Dornase alfa is available only with your doctor's prescription, in the following dosage form:

Inhalation
• Inhalation solution (U.S. and Canada)

Brand Names

Some commonly used brand names are:

In the U.S. -

• Pulmozyme

In Canada -

• Pulmozyme

Other commonly used names are: rhDNase and DNase I .