Miglustat (Systemic)
Brand Names : Zavesca
Category- Substrate reduction
therapy
DescriptionMiglustat ((MIH-glue-stat))
is used to treat
adults with mild to moderate type 1Gaucher disease. Miglustat is only used
in people who cannot be treated with enzyme replacement therapy. Type 1 Gaucher
disease is a disease you get from both your parents. People with type 1 Gaucher
disease are missing an enzyme (naturally occurring substance in your body)
that breaks down a chemical in your body called glucosylceramide. Too much
glucosylceramide causes liver and spleen enlargement, changes in the blood,
and bone disease. Miglustat works by stopping the body from making glucosylceramide.
This medicine is available only with your doctor's prescription, in the
following dosage forms:
Brand NamesSome commonly used brand names are:
In the U.S. -
† Not commercially available in Canada.
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