Trimetrexate (Systemic)

Brand Names : Neutrexin

Category

• Antiprotozoal
• antineoplastic

Description

Trimetrexate (tri-me-TREX-ate) is used, together with leucovorin (loo-koe-VOR-in), to treat Pneumocystis carinii ((noo-moe-SISS-tis)) pneumonia (PCP), a very serious kind of pneumonia. This kind of pneumonia occurs commonly in patients whose immune system is not working normally, such as cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).

Trimetrexate may cause some serious, even life-threatening, side effects. To prevent these effects, you must take another medicine, leucovorin, together with trimetrexate and for 3 days after you stop receiving trimetrexate. Before you begin treatment with trimetrexate, you and your doctor should talk about the good this medicine will do as well as the risks of using it.

Trimetrexate is to be administered only by or under the immediate supervision of your doctor. It is available in the following dosage form:

Parenteral
• Injection (U.S. and Canada)

Brand Names

Some commonly used brand names are:

In the U.S. -

• Neutrexin

In Canada -

• Neutrexin