Goodpasture Syndrome (Anti-GBM Antibody Disease)

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Goodpasture Syndrome

Alternate Names : Anti-GBM Antibody Disease

Overview, Causes, & Risk Factors | Symptoms & Signs | Diagnosis & Tests | Prevention & Expectations | Treatment & Monitoring

Goodpasture syndrome is a condition in which a person's own body attacks the lungs and kidneys. This may result in coughing up blood and rapid kidney failure.

What is going on in the body?

Goodpasture syndrome is a type of autoimmune disease, in which the person's body attacks its own tissue for unknown reasons. It occurs when a person's antibodies mistakenly attack the air-filled sacs of the lungs and the tiny filters in the kidneys. This can lead to rapid kidney failure and lung problems.

What are the causes and risks of the disease?

The cause of Goodpasture syndrome is unknown. It is more commonly seen in people who smoke, or have been exposed to hydrocarbons, such as gasoline and paint thinners.

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		Goodpasture Syndrome: Symptoms & Signs

Author: Rajnish K. Dhingra, MD
Reviewer: Linda Agnello, RN, BSN
Date Reviewed: 07/02/01

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