Nafarelin (Systemic)
Brand Names : Synarel
Category- Antiendometriotic agent
- gonadotropin inhibitor
- gonadotropin-releasing
hormone analog
DescriptionNafarelin (NAF-a-re-lin) is a hormone similar to the one normally released from
the hypothalamus gland in the brain. It is used in the treatment of:
-
Endometriosis, a painful condition caused by extra tissue similar
to the lining of the uterus growing inside and outside of the uterus.
-
Central precocious puberty (CPP), puberty developing too early in
boys and girls.
Nafarelin works by decreasing the amount of estrogen and testosterone
in the blood.
When given regularly to boys and girls, this medicine helps to prevent
them from continuing to develop the sexual features associated with puberty,
slowing down the development of breasts in girls and the development of genital
areas in boys and girls. This medicine delays puberty in a child only as long
as the child continues to take it.
Nafarelin prevents the growth of tissue associated with endometriosis in
adult women during treatment and for 6 months after treatment is discontinued.
Reducing the amount of estrogen in the body is one way of treating endometriosis.
Suppressing estrogen can thin the bones or slow their growth. This is a
problem for adult women whose bones are no longer growing like the bones of
children. Slowing the growth of bones is a positive effect for girls and boys
whose bones grow too fast when puberty begins too early. This is why nafarelin
is used only for up to 6 months in adult women treated for endometriosis,
but often is used for a longer time in girls and boys with pubertal problems.
Boys and girls may benefit by adding inches to their adult height when nafarelin
causes their bones to grow at a proper rate.
Nafarelin is available only with your doctor's prescription, in the following
dosage form:
Nasal
-
Solution (U.S. and Canada)
Brand NamesSome commonly used brand names are:
In the U.S. -
In Canada -
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